Osteoblast Ingrowth into Titanium Scaffolds made by Electron Beam MeltingShow others and affiliations
2014 (English)In: Materials Science Forum, ISSN 0255-5476, E-ISSN 1662-9752, Vol. 783-786, p. 1292-1297Article in journal (Refereed) Published
Abstract [en]
Present paper describes early findings from the study of Ti-6Al-4V scaffolds additively manufactured using electron beam melting (EBM®) technology and the influence of surface topography on the initial stages of cell acceptance. The surface topography of the components made by additive manufacturing (AM) processes including EBM® are often hard to control within the desired feature size range without post-processing. Two groups of experiments studying the behavior of human osteoblast-like cells (MG63) on samples with different surface roughness were carried out in vitro: Ti-6Al-4V samples only powder-blasted, and Ti-6Al-4V samples additionally electrochemically polished. The cell migration into powder-blasted Ti-6Al-4V 3D scaffolds with different shapes and dimensions of the lattice structures were studied.
Place, publisher, year, edition, pages
2014. Vol. 783-786, p. 1292-1297
Keywords [en]
titanium, electron beam melting, additive manufacturing, surface roughness, scaffold, biocompatibility, 3D cell culture, osteoblastic cells, RT-PCR
National Category
Other Mechanical Engineering
Identifiers
URN: urn:nbn:se:miun:diva-20590DOI: 10.4028/www.scientific.net/MSF.783-786.1292Scopus ID: 2-s2.0-84904542472OAI: oai:DiVA.org:miun-20590DiVA, id: diva2:677556
Conference
8th International Conference on Processing and Manufacturing of Advanced Materials, THERMEC 2013; Las Vegas, NV; United States; 2 December 2013 through 6 December 2013; Code 105675
2013-12-102013-12-102025-09-25Bibliographically approved