Acceptance and Commitment Therapy (ACT) has demonstrated promising outcomes to date with clinical populations affected by psychosis, however there is a dearth of such investigations involving non-clinical samples despite evidence that symptoms of psychosis exist on a continuum in the general population. The present study aimed to investigate how key ACT processes relate to psychosis-like symptoms in the general population. A convenience sample of 77 adults completed self-report measures of cognitive fusion, mindfulness, experiential avoidance, and psychosis-like symptoms, and relative distress, intrusiveness and frequency. A series of correlational and hierarchical regression analyses investigated the relationship between target variables. Higher mindfulness was related to lower levels of psychosis-like symptoms as well as lower distress, intrusiveness, and frequency in relation to these experiences, as were lower levels of cognitive fusion and experiential avoidance. Higher levels of cognitive fusion and experiential avoidance, as well as lower levels mindfulness, emerged as significant predictors of higher levels of psychosis-like symptoms, and higher relative distress, intrusiveness, and frequency. Findings are discussed in relation to implications for future clinical research.