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On the use of iron in organic chemistry
Stockholm University.
Mid Sweden University, Faculty of Science, Technology and Media, Department of Natural Sciences. Stockholms Universitet.
2020 (English)In: Molecules, ISSN 1431-5157, E-ISSN 1420-3049, Vol. 25, no 6, article id 25061349Article in journal (Refereed) Published
Abstract [en]

Transition metal catalysis in modern organic synthesis has largely focused on noble transition metals like palladium, platinum and ruthenium. The toxicity and low abundance of these metals, however, has led to a rising focus on the development of the more sustainable base metals like iron, copper and nickel for use in catalysis. Iron is a particularly good candidate for this purpose due to its abundance, wide redox potential range, and the ease with which its properties can be tuned through the exploitation of its multiple oxidation states, electron spin states and redox potential. This is a fact made clear by all life on Earth, where iron is used as a cornerstone in the chemistry of living processes. In this mini review, we report on the general advancements in the field of iron catalysis in organic chemistry covering addition reactions, C-H activation, cross-coupling reactions, cycloadditions, isomerization and redox reactions. 

Place, publisher, year, edition, pages
2020. Vol. 25, no 6, article id 25061349
Keywords [en]
C-C coupling, C-H activation, Iron, Organic synthesis
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:miun:diva-38770DOI: 10.3390/molecules25061349ISI: 000530248700092Scopus ID: 2-s2.0-85081655015OAI: oai:DiVA.org:miun-38770DiVA, id: diva2:1420937
Available from: 2020-04-01 Created: 2020-04-01 Last updated: 2025-09-25

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Bäckvall, Jan-Erling

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  • apa
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