Mid Sweden University

miun.sePublications
System disruptions
There are recurring service disruptions on some of the search portals due to high traffic. We are working to resolve the issue, you may temporarily encounter an error message.
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A Gaussian fitting-based analysis method for multiple image radiography with integrated angular calibration, MIR2
Mid Sweden University, Faculty of Science, Technology and Media, Department of Computer and Electrical Engineering (2023-). University of Saskatchewan, Canada.ORCID iD: 0009-0002-6915-3892
Mid Sweden University, Faculty of Science, Technology and Media, Department of Computer and Electrical Engineering (2023-).ORCID iD: 0000-0002-5619-409X
Mid Sweden University, Faculty of Science, Technology and Media, Department of Computer and Electrical Engineering (2023-).ORCID iD: 0000-0001-9334-3958
Show others and affiliations
2025 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 70, no 23, article id 235032Article in journal (Refereed) Published
Abstract [en]

Multiple image radiography (MIR) is an X-ray phase-contrast technique that enhances soft-tissuevisibility by rejecting Compton scatter and capturing absorption, refraction, and ultra-smallangle x-ray scattering (USAXS) signals. Conventional MIR workflows depend on normalizationbetween object and reference datasets and precise angular alignment, making them sensitive todrift and prone to artifacts such as banding. We present an improved analysis framework, MIR2,which eliminates normalization and alignment by independently analyzing object and referencedata and applying angular calibration based on the dynamical theory of diffraction. Like MIR, itemploys pixel-wise Gaussian fitting of angular intensity profiles, but the MIR2 pipeline is simpler,less error-prone, and more robust against alignment-related artifacts. Importantly, artifact suppression is achieved intrinsically, without relying on additional correction algorithms. MIR2 wasimplemented in Python and validated at the BMIT beamline (Canadian Light Source, 33.3 keV,Si(220) double-crystal monochromator) using both test objects (PMMA step wedge, layeredpaper) and in vivo imaging of a live anesthetized mouse lung. Across both studies, MIR2 producedmore stable and artifact-reduced images than MIR. The method simplifies analysis workflows andsupports streamlined application of MIR in biomedical and material imaging under dose-limitedconditions. 

Place, publisher, year, edition, pages
IOP Publishing , 2025. Vol. 70, no 23, article id 235032
National Category
Medical Imaging
Identifiers
URN: urn:nbn:se:miun:diva-56161DOI: 10.1088/1361-6560/ae22baISI: 001630896400001PubMedID: 41270370Scopus ID: 2-s2.0-105023843367OAI: oai:DiVA.org:miun-56161DiVA, id: diva2:2019912
Available from: 2025-12-09 Created: 2025-12-09 Last updated: 2025-12-16Bibliographically approved

Open Access in DiVA

fulltext(5063 kB)118 downloads
File information
File name FULLTEXT01.pdfFile size 5063 kBChecksum SHA-512
4079d610cd7ea8d7978b07b568a18e85ed3f1c9b1c1fde042fae01fd2bfe2861ee3b002176e08d554c4aba71658ac0e6ed45f3edd46f7d4ea18e4620792b16ff
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Foroughi, FarangisKrapohl, DavidNorlin, BörjeMenk, Ralf Hendrik

Search in DiVA

By author/editor
Foroughi, FarangisAulakh, GurpreetKrapohl, DavidNorlin, BörjeMenk, Ralf HendrikChapman, Dean
By organisation
Department of Computer and Electrical Engineering (2023-)
In the same journal
Physics in Medicine and Biology
Medical Imaging

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 806 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf