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Heterogeneous copper-catalyzed Grignard reactions with allylic substrates
Stockholm Univ, Dept Organ Chem, Arrhenius Lab, SE-10691 Stockholm, Sweden..
Mid Sweden University, Faculty of Science, Technology and Media, Department of Engineering, Mathematics, and Science Education (2023-).
Mid Sweden University, Faculty of Science, Technology and Media, Department of Engineering, Mathematics, and Science Education (2023-).ORCID iD: 0000-0001-9620-8698
Stockholm Univ, Dept Organ Chem, Arrhenius Lab, SE-10691 Stockholm, Sweden..ORCID iD: 0000-0001-7928-1877
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2025 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 61, no 13, p. 2802-2805Article in journal (Refereed) Published
Abstract [en]

Herein, we present a highly efficient allylic substitution of carbonates with Grignard reagents using a reusable cellulose-supported nanocopper catalyst. This approach highlights the first instance of heterogeneous catalysis for the cross-coupling of allylic alcohol substrates with Grignard reagents. The method features high yields, excellent regioselectivity, and complete chirality transfer.

Place, publisher, year, edition, pages
Royal Society of Chemistry (RSC) , 2025. Vol. 61, no 13, p. 2802-2805
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Organic Chemistry
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URN: urn:nbn:se:miun:diva-53721DOI: 10.1039/d4cc05366dISI: 001400888900001PubMedID: 39836020Scopus ID: 2-s2.0-85215988059OAI: oai:DiVA.org:miun-53721DiVA, id: diva2:1933982
Available from: 2025-02-03 Created: 2025-02-03 Last updated: 2025-09-25

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Deiana, LucaCordova, ArmandoBäckvall, Jan-Erling

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Deiana, LucaCordova, ArmandoWu, HaiboBäckvall, Jan-Erling
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Chemical Communications
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