This study combines a media content analysis (N = 1158) and panel survey data (N = 1612) conducted during the Swedish 2010 national election campaign, to analyze the effects of both game-framed and issue-framed news on political cynicism, institutional trust, and political interest. The findings show that news framing matters. Whereas game-framed news increases cynicism and depresses interest, issue-framed news has mobilizing effects. Furthermore, by conceptually and empirically distinguishing frame exposure from motivated news attention as two different modes of news media use, the results show that the effects of exposure to game-framed and issue-framed news are distinct from motivated news attention. These findings suggest two different mechanisms behind media effects and shine new light on the spiral of cynicism-virtuous circle controversy.