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  • 1.
    Douglas, T
    et al.
    LANCASTER UNIVERSITY, UK.
    Hempel, U
    INSTITUTE OF PHYSIOLOGICAL CHEMISTRY, TECHNISCHE UNIVERSITÄT DRESDEN, GERMANY.
    Żydek, J
    AGH UNIVERSITY OF SCIENCE AND TECHNOLOGY, KRAKOW, POLAND.
    Buchweitz, M
    TOMSK POLYTECHNIC UNIVERSITY, RUSSIA.
    Surmenev, Roman
    Tomsk Polytechnic University, Tomsk, Russia.
    Surmeneva, Maria
    Tomsk Polytechnic University, Tomsk, Russia.
    Koptioug, Andrey
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics. SportsTech Research Centre, Mid Sweden University.
    Pamula, E
    AGH UNIVERSITY OF SCIENCE AND TECHNOLOGY, KRAKOW, POLAND.
    Pectin Coatings on Titanium Alloy Samples Produced by Additive Manufacturing: Promotion of Human Bone Marrow Stromal Cell Proliferation2017In: Engineering of Biomaterials, ISSN 1429-7248, Vol. 143, p. 43-Article in journal (Refereed)
  • 2.
    Koptyug, Andrey
    et al.
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Engineering and Sustainable Development.
    Rännar, Lars-Erik
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Engineering and Sustainable Development.
    Backstrom, Mikael
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Engineering and Sustainable Development.
    Klingvall, Rebecca
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Engineering and Sustainable Development.
    Electron Beam Melting: Moving from Macro- to Micro- and Nanoscale2012In: Materials Science Forum, Switzerland: Trans Tech Publications Inc., 2012, Vol. 706-709, p. 532-537Conference paper (Refereed)
    Abstract [en]

    This paper presents some results achieved in the biomedical applications of the EBM® technology, and describes the resolved and unresolved challenges presented by modern medical implant manufacturing. In particular it outlines the issues related to the cellular structure design and metal surface modification. Moving to precision control of the metal surface at a microand sub-micrometer scale is a serious challenge to the EBM® processing, because it uses the powder with average grain size of about 0.04 to 0.1 mm. Though manufacturing of components with solidmesh geometry and porous surfaces using EBM® is quite possible, post- processing (for example chemical or electrochemical) is needed to achieve desired control of the surface at smaller scales to realize full potential of the technology for biomedical applications.

  • 3.
    Persson, Johan
    et al.
    Uppsala universitet.
    Helgason, Benedikt
    Institute for Biomechanics, Zürich, Switzerland.
    Engqvist, Håkan
    Uppsala universitet.
    Ferguson, Stephen J.
    Institute for Biomechanics, Zürich, Switzerland.
    Persson, Cecilia
    Uppsala universitet.
    Stiffness and strength of cranioplastic implant systems in comparison to cranial bone2018In: Journal of Cranio-Maxillofacial Surgery, ISSN 1010-5182, E-ISSN 1878-4119, Vol. 46, no 3, p. 418-423Article in journal (Refereed)
    Abstract [en]

    Purpose: The aim of this study was to evaluate skull replacement options after decompressive craniectomy by systematically investigating which combination of geometrical properties and material selection would result in a mechanical response comparable in stiffness to that of native skull bone and a strength as high or higher than the same.

    Materials and methods: The study was conducted using a Finite Element Model of the top part of a human skull. Native skull bone, autografts and commercial implants made of PEEK, solid titanium, two titanium meshes and a titanium-ceramic composite were modeled under a set load to evaluate deformation and maximum stress.

    Results: The computational result showed a large variation of the strength and effective stiffness of the autografts and implants. The stiffness of native bone varied by a factor of 20 and the strength by a factor of eight. The implants span the entire span of the native skull, both in stiffness and strength.

    Conclusion: All the investigated implant materials had a potential for having the same effective stiffness as the native skull bone. All the materials also had the potential to be as strong as the native bone. To match inherent properties, the best choice of material and thickness is thus patient specific, depending on the quality of the patient’s native bone.

  • 4.
    Surmenev, Roman
    et al.
    Tomsk Polytechnic University, Tomsk, Russia.
    Surmeneva, Maria
    Tomsk Polytechnic University, Tomsk, Russia.
    Chudinova, Ekaterina
    Tomsk Polytechnic University, Tomsk, Russia.
    Koptioug, Andrei
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics.
    Melnikova, E.S.
    Skoglund, Per
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics.
    Prymak, O.
    Epple, M.
    Wittmar, A.
    Ulbricht, M
    Surface modification of additive manufactured titanium with CaP, Ag nanoparticles and ultrathin HA coating2016In: Proceedings BIOMAH-2016, 2016Conference paper (Refereed)
  • 5.
    Surmeneva, Maria
    et al.
    Tomsk Polytechnic University, Institute of Physics and Technologies, Lenina ave., 30, Tomsk, Russian Federation .
    Chudinova, Ekaterina
    Tomsk Polytechnic University, Institute of Physics and Technologies, Lenina ave., 30, Tomsk, Russian Federation .
    Syrtanov, M
    Tomsk Polytechnic University, Institute of Physics and Technologies, Lenina ave., 30, Tomsk, Russian Federation .
    Koptyug, Andrey
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics.
    Surmenev, Roman
    Tomsk Polytechnic University, Institute of Physics and Technologies, Lenina ave., 30, Tomsk, Russian Federation .
    Investigation of the HA film deposited on the porous Ti6Al4V alloy prepared via additive manufacturing2015In: IOP Conference Series: Materials Science and Engineering, IOP, 2015, Vol. 98, p. Art. no. 012025-, article id 012025Conference paper (Refereed)
    Abstract [en]

    This study is focused on the use of radio frequency magnetron sputtering to modify the surface of porous Ti6Al4V alloy fabricated via additive manufacturing technology. The hydroxyapatite (HA) coated porous Ti6Al4V alloy was studied in respect with its chemical and phase composition, surface morphology, water contact angle and hysteresis, and surface free energy. Thin nanocrystalline HA film was deposited while its structure with diamond-shaped cells remained unchanged. Hysteresis and water contact angle measurements revealed an effect of the deposited HA films, namely an increased water contact angle and contact angle hysteresis. The increase of the contact angle of the coating-substrate system compared to the uncoated substrate was attributed to the multiscale structure of the resulted surfaces.

  • 6.
    Vladescu, Alina
    et al.
    National Institute for Optoelectronics, Romania; National Research Tomsk Polytechnic University, Lenin Avenue 43, Tomsk, Russian Federation.
    Vranceanu, Diana
    University Politehnica of Bucharest, Romania.
    Kulesza, Slawek
    Warmia and Mazury University in Olsztyn, Poland.
    Ivanov, Alexey
    Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery, Russia.
    Bramowicz, Mirosław
    Warmia and Mazury University in Olsztyn, Poland.
    Fedonnikov, Alexander
    Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery, Russia.
    Braic, Mariana
    National Institute for Optoelectronics, Romania.
    Norkin, Igor
    Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery, Russia.
    Koptioug, Andrei
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics.
    Kurtukova, Maria O.
    Saratov State Medical University, Russia.
    Dinu, Mihaela
    National Institute for Optoelectronics, Romania.
    Pana, Iulian
    National Institute for Optoelectronics, Romania.
    Surmeneva, Maria
    Tomsk Polytechnic University, Tomsk, Russia.
    Surmenev, Roman A.
    Tomsk Polytechnic University, Tomsk, Russia.
    Cotrut, Cosmin M.
    University Politehnica of Bucharest, Romania; Natl Res Tomsk Polytech Univ, Tomsk, Russia.
    Influence of the electrolyte’s pH on the properties of electrochemically deposited hydroxyapatite coating on additively manufactured Ti64 alloy2017In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 7, no 1, article id 16819Article in journal (Refereed)
    Abstract [en]

    Properties of the hydroxyapatite obtained by electrochemical assisted deposition (ED) are dependenton several factors including deposition temperature, electrolyte pH and concentrations, appliedpotential. All of these factors directly influence the morphology, stoichiometry, crystallinity,electrochemical behaviour, and particularly the coating thickness. Coating structure together withsurface micro- and nano-scale topography significantly influence early stages of the implant biointegration.The aim of this study is to analyse the effect of pH modification on the morphology,corrosion behaviour and in vitro bioactivity and in vivo biocompatibility of hydroxyapatite preparedby ED on the additively manufactured Ti64 samples. The coatings prepared in the electrolytes withpH = 6 have predominantly needle like morphology with the dimensions in the nanometric scale(~30 nm). Samples coated at pH = 6 demonstrated higher protection efficiency against the corrosiveattack as compared to the ones coated at pH = 5 (~93% against 89%). The in vitro bioactivity resultsindicated that both coatings have a greater capacity of biomineralization, compared to the uncoatedTi64. Somehow, the coating deposited at pH = 6 exhibited good corrosion behaviour and highbiomineralization ability. In vivo subcutaneous implantation of the coated samples into the white rats for up to 21 days with following histological studies showed no serious inflammatory process.

  • 7. Vranceanu, D.M.
    et al.
    Koptioug, Andrei
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics.
    Vladescu, Alina
    Braic, M
    Surmenev, Roman
    Tomsk Polytechnic University, Tomsk, Russia.
    Surmeneva, Maria
    Tomsk Polytechnic University, Tomsk, Russia.
    Berbecaru, A
    Cotrut, Cosmin
    Biofunctionalization of porous Ti6Al4V with HAp coatings obtained by electrochemical assisted deposition2016In: Proc. 7 th International Conference “Biomaterials, Tissue Engineering & Medical Devices” BIOMMEDD’2016, 2016Conference paper (Refereed)
1 - 7 of 7
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