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  • 1.
    Hreinsdottir, J.
    et al.
    Department of Neuroscience/Ophthalmology, University Hospital, Uppsala 75895, Sweden .
    Ewald, U.
    Department of Womens and Childrens Health, Uppsala University, Uppsala, Sweden .
    Strand Brodd, K.
    Department of Womens and Childrens Health, Uppsala University, Uppsala, Sweden .
    Örnkloo, Helena
    Mid Sweden University, Faculty of Human Sciences, Department of Psychology.
    Von Hofsten, C.
    Department of Psychology, Uppsala University, Uppsala, Sweden.
    Holmström, G.
    Department of Neuroscience/Ophthalmology, University Hospital, Uppsala 75895, Sweden .
    Ophthalmological outcome and visuospatial ability in very preterm children measured at 2.5 years corrected age2013In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 102, no 12, p. 1144-1149Article in journal (Refereed)
    Abstract [en]

    Aim To investigate the ophthalmological outcome of very preterm children at 2.5 years corrected age (CA) and perform a test of visuospatial and cognitive abilities. Methods A population-based, prospective study (LOVIS study) in Uppsala County, Sweden, comprised 111 very preterm children (<32 w gestational age [GA]) born between 1 January 2004 and 31 December 2007. Ophthalmic evaluations were undertaken in 98/109 children (89.9%) alive at 2.5 years. Spatial cognition was investigated with a test of five alternative blocks in 48 preterm and 25 term-born children. Results Visual impairment, strabismus or refractive errors, were found in 12% of the children. None of the children were blind in both eyes. Logistic regression analyses revealed significant associations between strabismus and periventricular leucomalacia/ intraventricular haemorrhage (OR 9.6, p = 0.025) and between refractive errors and severe retinopathy of prematurity (OR 9.8, p = 0.011) and GA (OR 0.763, p = 0.034). Oval and rectangular blocks were significantly more difficult to insert into a box for preterm than full-term children (p = 0.048 and 0.013, respectively). There was a significant correlation between total scores for the five blocks and GA at birth (p = 0.035). Conclusion Eye and visual problems were found in 12% of the preterm children at 30 months CA. Preterm children had difficulties with blocks of complex shapes. ©2013 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd.

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