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  • 1101.
    Åkerlund, Ann
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Albertsson, Elisabet
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Livet efter en hjärtinfarkt: Hur påverkas patient och familj?2013Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund:Hjärtinfarkt är den vanligaste orsaken till dödsfall i Sverige. Att drabbas av akut sjukdom är en kritisk upplevelse för både patient och närstående vilket leder till ett behov av stöd för hela familjen. Syfte: Att belysa den mentala hälsan hos personer som har drabbats av en hjärtinfarkt samt återhämtningsprocessen. Metod: Litteraturöversikt där vetenskapliga artiklar via databaserna Pubmed, Psykinfo och Cinahl granskats. Utifrån artikelgranskningen uppkom tre kategorier; Den mentala hälsan och reaktioner hos patienter som drabbats av hjärtinfarkt, Återhämtningsprocessen efter en hjärtinfarkt samt Sjukvårdens roll i återhämtningsprocessen. Resultat: Reaktioner hos patienter som har drabbats av hjärtinfarkt varierar, depression drabbar cirka 50 %. Överlevnad var av central betydelse efter hjärtinfarkten. Familjen ansågs vara värdefullt stöd i återhämtningsprocessen men hade också risk att bli alltför överbeskyddande. Personal inom primärvården underskattade förekomsten av depression. Individuell rådgivning ger en bättre livskvalité. Diskussion: Vårdpersonal måste se hela människan, patienten ska ses som en individ med med individuella förutsättningar till återhämtning och vården bör planeras därefter. Tydlig information är av stor vikt till både patient och närstående ska involveras mer i vården. Slutsats: Patientens mentala hälsan har stor inverkan på återhämtningsprocessen. Framtida forskning inom området bör fokusera på i hur mycket kunskap sjuksköterskor har om patienters psykiska hälsa efter en hjärtinfarkt.

  • 1102.
    Åkerlund, Daniel
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Arbetsrelaterad stress bland hemtjänstpersonal och underlättande faktorer i arbetet: -en kvalitativ intervjustudie2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1103.
    Åkerstedt, Torbjörn
    et al.
    Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
    Knutsson, Anders
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Narusyte, Jurgita
    Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
    Svedberg, Pia
    Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
    Kecklund, Goran
    Radboud Univ Nijmegen, Behav Sci Inst, NL-6525 ED Nijmegen, Netherlands.
    Alexanderson, Kristina
    Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
    Night work and breast cancer in women: a Swedish cohort study2015In: BMJ Open, ISSN 2044-6055, E-ISSN 2044-6055, Vol. 5, no 4, article id e008127Article in journal (Refereed)
    Abstract [en]

    Objectives: Recent research has suggested a moderate link between night work and breast cancer in women, mainly through case-control studies, but nonsignificant studies are also common and cohort studies are few. The purpose of the present study was to provide new information from cohort data through investigating the association between the number of years with night work and breast cancer among women. Design: Cohort study of individuals exposed to night shift work in relation to incidence of breast cancer in women. Setting: Individuals in the Swedish Twin registry, with follow-up in the Swedish Cancer Registry. Participants: 13 656 women from the Swedish Twin Registry, with 3404 exposed to night work. Outcome measures: Breast cancer from the Swedish Cancer Registry (463 cases) during a follow-up time of 12 years. Results: A Cox proportional hazards regression analysis with control for a large number of confounders showed that the HR was HR=1.68 (95% CI 0.98 to 2.88) for the group with >20 years of night work. When the follow-up time was limited to ages below 60 years, those exposed >20 years showed a HR=1.77 (95% CI 1.03 to 3.04). Shorter exposure to night work showed no significant effects. Conclusions: The present results, together with previous work, suggest that night work is associated with an increased risk of breast cancer in women, but only after relatively long-term exposure.

  • 1104.
    Ålander, Åsa
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    En Kvalitativ studie om hemtjänstpersonalens upplevelser i Vanguardmetoden.: - I jämförelse med tidigare arbetssätt.2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1105.
    Ålund, Jennifer
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Depressiva symptom, skolprestationer och betyg-Påverkas ungomars psykiska välmående av skolrelaterade faktorer?2015Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
  • 1106.
    Åsberg, Maria
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Enhetschefens upplevelse av hälsofrämjande ledarskap - En kvalitativ studie inom primärvården/Landstinget i Mellansverige.2014Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
  • 1107.
    Åslin, Erik
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    “The development of a new reactive agility test for soccer”2017Independent thesis Advanced level (degree of Master (One Year)), 20 HE creditsStudent thesis
    Abstract [sv]

    Fotboll är en intermittent sport med både offensiva och defensiva aktioner som kräver ett flertal höghastighetsrörelser (sprint, vändningar) som respons till yttre stimuli vilket betonar betydelsen av att träna och testa agility (kvickhet). Syfte med denna studie var att a) konstruera ett nytt fotbollspecifikt reaktivt agility-test, b) utvärdera reliabiliteten och validiteten av de nya testerna och c) undersöka eventuellt samband mellan fysiska egenskaper (snabbhet, effektutveckling/explosivitet, styrka) och snabbhetstest med riktningsförändringar (CODS) och förmåga till reaktiv agility (RA). Tjugo unga manliga fotbollsspelare (ålder: 17,0 ± 0,9 år; kroppslängd: 1,81 ± 0,03 m; kroppsvikt: 70,0 ± 7,4 kg; kroppsfett 11,3 ± 2,0 %) delades upp i två grupper (10 spelare per grupp) baserat på ålder och fotbollsprestation (U17 & U19). Reliabilitetsdata visade hög tillförlitlighet för de båda CODS och RA-testerna (ICC-koefficienter 0,92 och 0,70-0,88). Within-subject variabiliteten hade en variationsvidd emellan 3,6–5,8 %. Ett moderat samband mellan CODS och RA-protokollen indikerar på en låg samhörighet. Regressionsanalyserna visade att de testade fysiska kvaliteterna inte kunde användas för att förutsäga resultaten i CODS och/eller de andra RA-testerna. Oberoende t-test visade att den högre rankade gruppen var bättre i både CODS och två andra RA-tester. Sammanfattningsvis, påvisade de nykonstruerande testerna god reliabilitet och validitet för test av unga fotbollsspelare. I tillägg, visade sig CODS och RA vara två oberoende kvaliteter och bör tränas och testat separat.

  • 1108.
    Åström, Amanda
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Strikt lågkolhydratskost som rehabiliteringsmetod vid typ 2 diabetes: – konsekvenser för livskvalité och arbetsliv2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1109.
    Åström, Ingrid
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Upplevd arbetstillfredsställese för undersköterskor vid LSS-boende: En kvalitativ studie om vad undersköterskorna upplevde krävdes för att ge bra stöd till de boende.2018Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
  • 1110.
    Öberg, Petra
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Psykisk ohälsa hos äldre, hur påverkar fysisk aktivitet?Personalens upplevelser.2017Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
  • 1111.
    Ögren, Tsuyu
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Regulatory Inspectors and their Work Environment: A Thematic Analysis2017Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1112.
    Öhrberg, Petra
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Psykisk ohälsa hos ädre, hur påverkar fysisk aktivitet?Personalens upplevelser.2017Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
  • 1113.
    Öjefors Stark, Katarina
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Faktorer som kopplas till självskattad hälsa bland äldre i Västernorrland: En tvärsnittstudie baserad på befolkningsundersökningen Hälsa på lika villkor.2018Student paper other, 10 credits / 15 HE creditsStudent thesis
  • 1114.
    Örtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Hvid, Lars G
    University of Southern Denmark, Odense, Denmark.
    Jensen, Rasmus
    University of Southern Denmark, Odense, Denmark.
    Andersson, Erik
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Willis, Sarah J
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Holmberg, Hans-Christer
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Gejl, Kasper D
    University of Southern Denmark, Odense, Denmark.
    Repeated sprint exercise impairs contractile force of isolated single human muscle fibers2013In: Proceedings for the 6th International Congress on Science and Skiing / [ed] Erich Mueller, Josef Kröll, Stefan Josef Lindinger, Jurgen Pfusterschmied, Thomas Stöggl, 2013, p. 93-Conference paper (Refereed)
    Abstract [en]

    INTRODUCTION: The purpose of the present study was, to examine the effects of repeated sprint skiing on the contractile apparatus of single muscle fibres obtained from a group of elite skiers. We have recently demonstrated that prolonged cycling exercise impairs the contractile apparatus of single muscle fibres, and that this can be restored following recovery. However, little is known about the effect of repeated high intensity exercise on single fibre properties, as i.e. during cross-country (cc) sprint competitions. We hypothesize that repeated high intensity exercise in highly trained subjects will impair the contractile apparatus maximum force output.

    METHOD: Eleven elite male sprint talented cc skiers (age 24 ± 4 years; VO2max 5.1 ± 0.5 (diagonal skiing, DIA), 4.9 ± 0.5 (double pooling, DP) L·min-1)) volunteered for the study. The skiers performed a simulated intermittent classic sprint roller skiing competition on a treadmill. The sprint exercise included 4 times1300m, with 45 min recovery between sprints. Each sprint consisted of 3 DP sections (1° uphill) and 2 DIA sections (7° uphill). Muscle biopsies were obtained in arm muscle (m. biceps brachii) before and after the sprint exercises. Muscle fibre bundles were cooled and skinned in a glycerinating solution and stored until analyzed. Single muscle fibre segments (n=232) were isolated and attached to a sensitive force recording transducer, and activated by Ca2+ buffered solutions at pH 7.1 to measure mechanically properties (maximum force Po and Po/cross sectional area (CSA)) and fibre typed by the Sr2+ sensitivity (Hvid et al. 2013).

    RESULTS: Average sprint time was 3min 49s ± 9s, with no difference between sprints. A total of 232 fibres were analysed (150 type I and 82 type II fibres). Type II fibres had a sign. (P<0.05) higher CSA (8103 ± 2334 µm2 (type I) and 8852 ± 2288 µm2 (type II) and Po (0.82 ± 0.43 and 1.24 ± 0.50 mN) than type I fibres. Also type II fibres had a 31% higher Po/CSA (108 ± 55 vs 142 ± 45 kN/m2). Following the intermittent sprint exercise, type II fibres exhibited a sign. (P = 0.01) 20% decrease in Po, with no difference in type I fibres. To test if the decrease in the single fibre Po were associated with oxidative stress we tested if this could be reversed with a strong reducing agent (dithiothreitol, DTT). DTT did not alter Po at pre nor the decrease in type II fibres following sprint exercise.

    DISCUSSION: By using a translational approach from whole body exercise to single fibre measurements, we here we demonstrate that type II fibres from highly trained cross country skiers, has a 20% decrease in Po following repeated sprint. Thus, part of the experienced fatigue following sprint competitions is due to impairments at the level of the contractile apparatus. Further, we did not find any evidence for oxidative stress as a causative component in the observed decrease in Po.

    CONCLUSION: Here we demonstrate for the first time, in highly trained sprint skiers, that repeated sprint impairs single fibre maximum force at the level of the contractile apparatus, which may have a significant impact on muscle function and fatigue.

    REFERENCES: Gejl K, Hvid LG, Ulrik Frandsen U, Jensen K, Sahlin K and Ørtenblad N. Muscle glycogen content modifies SR Ca2+ release rate in elite endurance athletes. Med. Sci. Sports Ex. (2013).

  • 1115.
    Örtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. Univ Southern Denmark, SDU Muscle Res Cluster, Dept Sports Sci & Clin Biomech, DK-5230 Odense, Denmark.;Mid Sweden Univ, Dept Hlth Sci, Swedish Winter Sports Res Ctr, Ostersund, Sweden..
    Nielsen, J.
    Univ Southern Denmark, SDU Muscle Res Cluster, Dept Sports Sci & Clin Biomech, DK-5230 Odense, Denmark..
    Muscle glycogen and cell function - Location, location, location2015In: Scandinavian Journal of Medicine and Science in Sports, ISSN 0905-7188, E-ISSN 1600-0838, Vol. 25, p. 34-40Article, review/survey (Refereed)
    Abstract [en]

    The importance of glycogen, as a fuel during exercise, is a fundamental concept in exercise physiology. The use of electron microscopy has revealed that glycogen is not evenly distributed in skeletal muscle fibers, but rather localized in distinct pools. In this review, we present the available evidence regarding the subcellular localization of glycogen in skeletal muscle and discuss this from the perspective of skeletal muscle fiber function. The distribution of glycogen in the defined pools within the skeletal muscle varies depending on exercise intensity, fiber phenotype, training status, and immobilization. Furthermore, these defined pools may serve specific functions in the cell. Specifically, reduced levels of these pools of glycogen are associated with reduced SR Ca2+ release, muscle relaxation rate, and membrane excitability. Collectively, the available literature strongly demonstrates that the subcellular localization of glycogen has to be considered to fully understand the role of glycogen metabolism and signaling in skeletal muscle function. Here, we propose that the effect of low muscle glycogen on excitation-contraction coupling may serve as a built-in mechanism, which links the energetic state of the muscle fiber to energy utilization.

  • 1116.
    Östling, Anders
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Samverkan inom vård och omsorg för de mest sjuka äldreFöutsättningar för samverkan mellan landsting och kommun i Västmanland2016Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
  • 1117.
    Östling, Carolina
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Vägen tillbaka mot innanförskap. Unga vuxnas upplevelser av avbrutna gymnasiestudier och resan tillbaka.2017Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 1118.
    Ørtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Gejl, Kasper D
    Holmberg, H-C
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Andersson, Erik
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Plomgaard, Peter
    Nielsen, Joachim
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Subcellular glycogen pools is utilized in a fibre type specific manner during acute and repeated high intensity exercise in elite athletes2016Conference paper (Refereed)
  • 1119.
    Ørtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Holmberg, Hans-Christer
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Schrøder, HD
    University of Southern Denmark, Odense, Denmark.
    Saltin, Bengt
    University of Copenhagen, Copenhagen, Denmark.
    Nielsen, Joachim
    University of Southern Denmark, Odense, Denmark.
    Differences in the mitochondrial content of different fibre types in the leg and arm muscles of elite cross-country skiers2013In: Proceedings for the 18th Annual Congress of the ECSS, 2013Conference paper (Refereed)
  • 1120.
    Ørtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Hvid, L
    University of Southern Denmark, Odense, Denmark.
    Jensen, R
    University of Southern Denmark, Odense, Denmark.
    Andersson, Erik
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Willis, Sarah
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Holmberg, Hans-Christer
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Gejl, K
    University of Southern Denmark, Odense, Denmark.
    Repeated sprint exercise affects contractile apparatus and force production of isolated human muscle fibers2014In: Science & Skiing VI / [ed] Erich Muller, Josef Kröll, Stefan Lindinger m.fl., Meyer & Meyer Sport, 2014, p. 446-452Chapter in book (Refereed)
  • 1121.
    Ørtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. University of Southern Denmark, Denmark.
    Jensen, Kurt
    University of Southern Denmark, Denmark.
    Gross efficiency predicts a 6-min double-poling ergometer performance in recreational cross-country skiers2017In: Sports Engineering, ISSN 1369-7072, E-ISSN 1460-2687, Vol. 20, no 4, p. 329-333Article in journal (Refereed)
    Abstract [en]

    The purpose of the study was to investigate which physiological parameters would most accurately predict a 6-min, all-out, double-poling (DP) performance in recreational cross-country skiers. Twelve male recreational cross-country skiers performed tests consisting of three series lasting 10 s, one lasting 60 s, plus a 6-min, all-out, DP performance test to estimate mean and peak power output. On a separate day, gross mechanical efficiency (GE) was estimated from a 10-min, submaximal, DP test and maximal oxygen consumption (VO2 max) was estimated from an incremental treadmill running test. Power was measured after each stroke from the acceleration and deceleration of the flywheel that induced the friction on the ergometer. The power was shown to the skier on a small computer placed on the ergometer. A multivariable correlation analysis showed that GE most strongly predicted 6-min DP performance (r = 0.79) and interestingly, neither DP VO2 max, nor treadmill-running VO2 max, correlated with 6-min DP performance. In conclusion, GE correlated most strongly with 6-min DP performance and GE at the ski ergometer was estimated to be 6.4 ± 1.1%. It is suggested that recreational cross-country skiers focus on skiing technique to improve gross mechanical efficiency during intense DP.

  • 1122.
    Ørtenblad, Niels
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. Univ Southern Denmark, Inst Sports Sci & Clin Biomech, SDU Muscle Res Cluster SMRC, DK-5230 Odense M, Denmark.
    Westerblad, Håkan
    Karolinska Inst, Dept Physiol & Pharmacol, SE-17177 Stockholm, Sweden.
    Nielsen, Joachim
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. Univ Southern Denmark, Inst Sports Sci & Clin Biomech, SDU Muscle Res Cluster SMRC, DK-5230 Odense M, Denmark.
    Muscle glycogen stores and fatigue2013In: Journal of Physiology, ISSN 0022-3751, E-ISSN 1469-7793, Vol. 591, no 18, p. 4405-4413Article, review/survey (Refereed)
    Abstract [en]

    Studies performed at the beginning of the last century revealed the importance of carbohydrate as a fuel during exercise, and the importance of muscle glycogen on performance has subsequently been confirmed in numerous studies. However, the link between glycogen depletion and impaired muscle function during fatigue is not well understood and a direct cause-and-effect relationship between glycogen and muscle function remains to be established. The use of electron microscopy has revealed that glycogen is not homogeneously distributed in skeletal muscle fibres, but rather localized in distinct pools. Furthermore, each glycogen granule has its own metabolic machinery with glycolytic enzymes and regulating proteins. One pool of such glycogenolytic complexes is localized within the myofibrils in close contact with key proteins involved in the excitation-contraction coupling and Ca2+ release from the sarcoplasmic reticulum (SR). We and others have provided experimental evidence in favour of a direct role of decreased glycogen, localized within the myofibrils, for the reduction in SR Ca2+ release during fatigue. This is consistent with compartmentalized energy turnover and distinctly localized glycogen pools being of key importance for SR Ca2+ release and thereby affecting muscle contractility and fatigability.

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