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  • 1.
    Lodin-Sundström, Angelica
    et al.
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Lunde, Alexander
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Palm, Oscar
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Nilsson, Simon
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Schagatay, Erika
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. Swedish Winter Sports Research Centre, Östersund, Sweden..
    Blood boosting by spleen contraction during exercise at different altitudes.2014Conference paper (Refereed)
    Abstract [en]

    Spleen contraction with release of erythrocytes improves human performance in hypoxic situations. Hypoxia and exercise are known to separately trigger the response. We studied the response to exercise at different altitudes during a two week ascent to 4200m. Eleven healthy lowlanders (five women; mean±SD age 26±3 years) did a modified Harvard step test at 1370, 3700 and 4200m altitude after 10 min rest. Spleen volume was measured via ultrasonic imaging and capillary hemoglobin (Hb) with Hemocue before and after tests. Mean(±SD) baseline spleen volume at 1370m was 250(±9)ml, after exercise it had been reduced to 207(±10)ml (P<0.01). At 3700m, baseline spleen volume was 230(±9)ml, after exercise 173(±10)ml (P<0.01). At 4200m baseline was 211(±10)ml, after exercise 158(±13)ml (P<0.05). Baseline Hb increased by altitude from 137.8(±3.8)g/L at 1370m, to 141.2(±2.3)g/L at 3700m and 151.4(±2.3)g/L at 4200m (P<0.01). At all locations Hb had increased after exercise; at 1370m by 7.2%, at 3700m by 6.2% and at 4200m by 3.2%. This suggests the spleen was already somewhat contracted during rest at higher altitudes, which was reflected by the progressively higher baseline Hb. Exercise initiated spleen contraction of similar magnitude at all altitudes, and post exercise values were progressively smaller with altitude. Hb was also elevated at all exercise tests, but not directly reflecting the spleen volume reductions, possibly due to differences in peak times. This study suggests that baseline spleen volume is affected by altitude which elevates Hb and that contraction after exercise results in further Hb elevation.

  • 2.
    Schagatay, Erika
    et al.
    Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
    Nilsson, Simon
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Palm, Oscar
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Lunde, Alexander
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Lodin-Sundström, Angelica
    Mid Sweden University, Faculty of Science, Technology and Media, Department of Ecotechnology and Sustainable Building Engineering.
    Can the cardiorespiratory response to exercise at altitude predict sensitivity to AMS?2014Conference paper (Refereed)
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