miun.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Muscle glycogen and cell function - Location, location, location
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. Univ Southern Denmark, SDU Muscle Res Cluster, Dept Sports Sci & Clin Biomech, DK-5230 Odense, Denmark.;Mid Sweden Univ, Dept Hlth Sci, Swedish Winter Sports Res Ctr, Ostersund, Sweden.. (Swedish Winter Sports Research Center)
Univ Southern Denmark, SDU Muscle Res Cluster, Dept Sports Sci & Clin Biomech, DK-5230 Odense, Denmark..
2015 (English)In: Scandinavian Journal of Medicine and Science in Sports, ISSN 0905-7188, E-ISSN 1600-0838, Vol. 25, 34-40 p.Article, review/survey (Refereed) Published
Resource type
Text
Abstract [en]

The importance of glycogen, as a fuel during exercise, is a fundamental concept in exercise physiology. The use of electron microscopy has revealed that glycogen is not evenly distributed in skeletal muscle fibers, but rather localized in distinct pools. In this review, we present the available evidence regarding the subcellular localization of glycogen in skeletal muscle and discuss this from the perspective of skeletal muscle fiber function. The distribution of glycogen in the defined pools within the skeletal muscle varies depending on exercise intensity, fiber phenotype, training status, and immobilization. Furthermore, these defined pools may serve specific functions in the cell. Specifically, reduced levels of these pools of glycogen are associated with reduced SR Ca2+ release, muscle relaxation rate, and membrane excitability. Collectively, the available literature strongly demonstrates that the subcellular localization of glycogen has to be considered to fully understand the role of glycogen metabolism and signaling in skeletal muscle function. Here, we propose that the effect of low muscle glycogen on excitation-contraction coupling may serve as a built-in mechanism, which links the energetic state of the muscle fiber to energy utilization.

Place, publisher, year, edition, pages
2015. Vol. 25, 34-40 p.
Keyword [en]
Glycogen granule, energy compartmentalization, exercise, E-C coupling
National Category
Sport and Fitness Sciences
Identifiers
URN: urn:nbn:se:miun:diva-26832DOI: 10.1111/sms.12599ISI: 000365322300012PubMedID: 26589115Scopus ID: 2-s2.0-84948405793OAI: oai:DiVA.org:miun-26832DiVA: diva2:891437
Available from: 2016-01-07 Created: 2016-01-07 Last updated: 2016-01-13Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Örtenblad, Niels
By organisation
Department of Health Sciences
In the same journal
Scandinavian Journal of Medicine and Science in Sports
Sport and Fitness Sciences

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 49 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf