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Proteomic approaches to identify circulating biomarkers in patients with abdominal aortic aneurysm
Mid Sweden University, Faculty of Science, Technology and Media, Department of Natural Sciences. (Analytisk kemi)ORCID iD: 0000-0002-3646-294X
Mid Sweden University, Faculty of Science, Technology and Media, Department of Natural Sciences. Sundsvalls sjukhus.
2015 (English)In: American Journal of Cardiovascular Disease, ISSN 2160-200X, Vol. 5, no 3, p. 140-145Article, review/survey (Refereed) Published
Resource type
Text
Abstract [en]

Abdominal aortic aneurysm (AAA) is a common condition with high mortality when ruptured. Most clinicians agree that small AAAs are best managed by ultrasonographic surveillance. However, it has been stated in recent reviews that a serum/plasma biomarker that predicts AAA rupture risk would be a powerful tool in stratifying patients with small AAAs. Identification of such circulating biomarkers with traditional hypothesis driven studies has been unsuccessful. In this review we summarize six studies using different proteomic approaches to find new, potential plasma AAA biomarker candidates. In conclusion, by using proteomic approaches novel potential plasma biomarkers for AAA have been identified.

Place, publisher, year, edition, pages
e-Century Publishing Corporation , 2015. Vol. 5, no 3, p. 140-145
Keywords [en]
Aortic aneurysm, biomarker, proteomics
National Category
Cardiac and Cardiovascular Systems Analytical Chemistry
Identifiers
URN: urn:nbn:se:miun:diva-26469ISI: 000364955400001PubMedID: 26417533OAI: oai:DiVA.org:miun-26469DiVA, id: diva2:882638
Available from: 2015-12-15 Created: 2015-12-15 Last updated: 2017-12-01Bibliographically approved

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PubMedhttp://www.ajcd.us/files/ajcd0009253.pdf

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Bylund, DanHenriksson, Anders E.

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CiteExportLink to record
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Citation style
  • apa
  • ieee
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  • Other style
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