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Osteoblast Ingrowth into Titanium Scaffolds made by Electron Beam Melting
Mid Sweden University, Faculty of Science, Technology and Media, Department of Quality Technology and Management, Mechanical Engineering and Mathematics. (SportsTech)
University Medical Center Rostock, Dept. of Cell Biology, Schillingallee 69, D-18057 Rostock, Germany.
Interface Research Group, Institute for Electronic Appliances and Circuits, University of Rostock, A.-Einstein-Str. 2, D-18059 Rostock, Germany.
University of Applied Sciences Northwestern Switzerland FHNW, School of Life Sciences, Gründenstrasse 40, CH-4132 Muttenz, Switzerland.
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2014 (English)In: Materials Science Forum, ISSN 0255-5476, E-ISSN 1662-9752, Vol. 783-786, p. 1292-1297Article in journal (Refereed) Published
Abstract [en]

Present paper describes early findings from the study of Ti-6Al-4V scaffolds additively manufactured using electron beam melting (EBM®) technology and the influence of surface topography on the initial stages of cell acceptance. The surface topography of the components made by additive manufacturing (AM) processes including EBM® are often hard to control within the desired feature size range without post-processing. Two groups of experiments studying the behavior of human osteoblast-like cells (MG63) on samples with different surface roughness were carried out in vitro: Ti-6Al-4V samples only powder-blasted, and Ti-6Al-4V samples additionally electrochemically polished. The cell migration into powder-blasted Ti-6Al-4V 3D scaffolds with different shapes and dimensions of the lattice structures were studied.

Place, publisher, year, edition, pages
2014. Vol. 783-786, p. 1292-1297
Keywords [en]
titanium, electron beam melting, additive manufacturing, surface roughness, scaffold, biocompatibility, 3D cell culture, osteoblastic cells, RT-PCR
National Category
Other Mechanical Engineering
Identifiers
URN: urn:nbn:se:miun:diva-20590DOI: 10.4028/www.scientific.net/MSF.783-786.1292Scopus ID: 2-s2.0-84904542472OAI: oai:DiVA.org:miun-20590DiVA, id: diva2:677556
Conference
8th International Conference on Processing and Manufacturing of Advanced Materials, THERMEC 2013; Las Vegas, NV; United States; 2 December 2013 through 6 December 2013; Code 105675
Available from: 2013-12-10 Created: 2013-12-10 Last updated: 2017-12-06Bibliographically approved

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Koptyug, AndreyRännar, Lars-Erik

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