miun.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Altitude attenuates apnea-induced increase in haemoglobin concentration
Mid Sweden University, Faculty of Science, Technology and Media, Department of Natural Sciences.
Mid Sweden University, Faculty of Science, Technology and Media, Department of Natural Sciences.
2007 (English)In: International Conference on Environmental Ergonomics, 2007Conference paper, Published paper (Other academic)
Abstract [en]

INTRODUCTION During apnea at sea-level, a contraction of the spleen is found in humans (Hurford et al 1990) causing a transient increase in hemoglobin concentration (Hb) and hematocrit (Schagatay et al 2001). The development of these increases is progressive across 3 serial apneas, typically resulting in Hb increases of 2% (Richardson et al, 2003), and recovery to pre-apneic values within 8-9 minutes (Schagatay et al 2005). The spleen contraction-associated Hb increase is in part triggered by the hypoxia occurring during apnea (Richardson et al 2005). The Hb increase leads to increased blood gas storage capacity which facilitates prolonged apnea in humans and may be responsible for the known prolongation of serial apneas (Schagatay et al 2001). At altitude, we suggest that the chronic hypoxia could induce splenic contraction during eupnea in humans, as previously observed in mice (Cook and Alafi 1956). Our aim was to reveal whether spleen related Hb increase occurs during eupneic altitude exposure in humans, thereby abolishing the Hb increase normally seen during apnea.

Place, publisher, year, edition, pages
2007.
Keyword [en]
Spleen, altitude, apnea, hemoglobin, hematocrit
National Category
Biological Sciences Sport and Fitness Sciences Microbiology
Identifiers
URN: urn:nbn:se:miun:diva-4362Local ID: 5528OAI: oai:DiVA.org:miun-4362DiVA: diva2:29394
Available from: 2008-09-30 Created: 2008-09-30 Last updated: 2011-04-12Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Richardson, MatthewSchagatay, Erika
By organisation
Department of Natural Sciences
Biological SciencesSport and Fitness SciencesMicrobiology

Search outside of DiVA

GoogleGoogle Scholar

Total: 130 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf