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Functional evaluation of microvascular free flaps with positron emission tomography
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
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2006 (English)In: Journal of Plastic, reconstructive & Aesthetic Surgery, ISSN 1748-6815, Vol. 59, no 2, 158-165 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The aim of this study was to assess blood flow (BF) of microvascular free flaps studied with positron emission tomography (PET) in patients with head and neck squamous cell cancer (HNSCC) undergoing major radical surgery 3-4 weeks after high-dose radiotherapy. METHODS: Five patients underwent resection of the HNSCC of the oral cavity followed by microvascular reconstruction with a radial forearm flap. Regional BF in oral and neck tissues was measured with PET using radiolabelled water ([(15)O]H(2)O) twice (1-2 and 12-14 days, respectively) following radical surgery. RESULTS: In the first postoperative PET study, the median BF in the cutaneous flap area was 5.1mL/100g/min, and in the muscle contra-lateral to the recipient site 19.9mL/100g/min. A low flap-to-muscle BF ratio appeared to correlate with circulatory incongruity, and thus with poorer flap success. The follow-up study on the second postoperative week supported the results of the primary PET scan. CONCLUSIONS: This pilot study suggests that PET using [(15)O]H(2)O is a feasible method to quantitatively evaluate BF of the whole free flap in patients operated on for oral HNSCC.

Place, publisher, year, edition, pages
2006. Vol. 59, no 2, 158-165 p.
Keyword [en]
PET, free flaps, blood flow, postoperative, head and neck cancer
Keyword [sv]
Idrottsvetenskap
National Category
Medical and Health Sciences Sport and Fitness Sciences
Identifiers
URN: urn:nbn:se:miun:diva-3718DOI: 10.1016/j.bjps.2005.04.016Local ID: 3882OAI: oai:DiVA.org:miun-3718DiVA: diva2:28750
Available from: 2008-09-30 Created: 2008-09-30Bibliographically approved

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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf