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Motion detection and correction for dynamic: 15O-water myocardial perfusion PET studies
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
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2005 (English)In: European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, Vol. 32, no 12, 1378-1383 p.Article in journal (Refereed) Published
Abstract [en]

Patient motion during dynamic PET studies is a well-documented source of errors. The purpose of this study was to investigate the incidence of frame-to-frame motion in dynamic ( 15)O-water myocardial perfusion PET studies, to test the efficacy of motion correction methods and to study whether implementation of motion correction would have an impact on the perfusion results. We tested manual, in-house-developed motion correction software and an automatic motion correction using a rigid body point model implemented in MIPAV (Medical Image Processing, Analysis and Visualisation) software. At rest, patient motion was found in 18% of the frames, but during pharmacological stress the fraction increased to 45% and during physical exercise it rose to 80%. Both motion correction algorithms significantly decreased (p<0.006) the number of moved frames and the amplitude of motion (p<0.04). Motion correction significantly increased MBF results during bicycle exercise (p<0.02). Applying motion correction for the data acquired during exercise clearly changed the MBF results, indicating that motion correction is required for these studies.

Place, publisher, year, edition, pages
2005. Vol. 32, no 12, 1378-1383 p.
Keyword [en]
PET, myocardial blood flow, motion detection, motion correction, physical exercise
National Category
Sport and Fitness Sciences
Identifiers
URN: urn:nbn:se:miun:diva-1352DOI: 10.1007/s00259-005-1846-4Local ID: 3885OAI: oai:DiVA.org:miun-1352DiVA: diva2:26384
Available from: 2008-09-30 Created: 2008-09-30Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
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  • modern-language-association-8th-edition
  • vancouver
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Language
  • de-DE
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  • fi-FI
  • nn-NO
  • nn-NB
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  • Other locale
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Output format
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  • asciidoc
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