The challenges regarding harmonised interoperable e-health services are enormous due to the complexity of the domain, comparatively high demands of privacy and security, implications of storing, sharing, and managing health data as well as unclear definitions and standards for patient's electronic health records. Therefore, the advantages of digitalisation are yet to reach the end user-patient, especially in the emergent regions where digital infrastructure is limited. The focus is on the north and northeast regions of Brazil, where a holistic understanding of the requirements for a digital transformation of the health care system is explored through the lens of an expert panel using a Delphi methodology, complemented by a comparison with related innovations in the digital health domain.