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The correlation between small papillary thyroid cancers and gamma radionuclides Cs-137, Th-232, U-238 and K-40 using spatially-explicit, register-based methods
Mid Sweden University, Faculty of Science, Technology and Media, Department of Natural Science, Design, and Sustainable Development (2023-).
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2023 (English)In: Spatial and Spatio-temporal Epidemiology, ISSN 1877-5845, E-ISSN 1877-5853, article id 100618Article in journal (Refereed) Published
Abstract [en]

A steep increase of small papillary thyroid cancers (sPTCs) has been observed globally. A major risk factor for developing PTC is ionizing radiation. The aim of this study is to investigate the spatial distribution of sPTC in Sweden and the extent to which prevalence is correlated to gamma radiation levels (Caesium-137 (Cs-137), Thorium-232 (Th-232), Uranium-238 (U-238) and Potassium-40 (K-40)) using multiple geospatial and geostatistical methods. The prevalence of metastatic sPTC was associated with significantly higher levels of Gamma radiation from Th-232, U-238 and K-40. The association is, however, inconsistent and the prevalence is higher in densely populated areas. The results clearly indicate that sPTC has causative factors that are neither evenly distributed among the population, nor geographically, calling for further studies with bigger cohorts. Environmental factors are believed to play a major role in the pathogenesis of the disease.

Place, publisher, year, edition, pages
Elsevier BV , 2023. article id 100618
Keywords [en]
Geographic information system (GIS), Papillary thyroid cancer, Radiation, Spatial analysis
National Category
Clinical Medicine Environmental Sciences Occupational Health and Environmental Health
Identifiers
URN: urn:nbn:se:miun:diva-49340DOI: 10.1016/j.sste.2023.100618ISI: 001083840000001Scopus ID: 2-s2.0-85171996339OAI: oai:DiVA.org:miun-49340DiVA, id: diva2:1799384
Available from: 2023-09-22 Created: 2023-09-22 Last updated: 2023-11-10Bibliographically approved

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van den Brink, PaulEnglund, Oskar

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Bayadsi, Haythamvan den Brink, PaulNordin, PärHennings, JoakimEnglund, Oskar
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Department of Natural Science, Design, and Sustainable Development (2023-)
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Spatial and Spatio-temporal Epidemiology
Clinical MedicineEnvironmental SciencesOccupational Health and Environmental Health

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CiteExportLink to record
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Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
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  • nn-NB
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More languages
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