The industrial Internet-of-things (IIoT) paradigm is reshaping the way industrial measurement systems are designed. Industrial systems require collecting accurate and timely measurements from the field using smart sensor networks distributed in wide production areas. In this context, wireless connectivity of sensors acquires undeniable importance, and in turn, opens sig-nificant research challenges. Therefore, the research community is actively analyzing the suitability of different wireless technologies, for instance, Wi-Fi, 5G-and-beyond, and low-power wide-area networks (LPWANs), toward their possible industrial applications and optimizing them to realize high-performance and accurate smart measurement systems. In this paper, we focus on long range (LoRa)-based LPWANs (i.e., LoRaWAN), especially to overcome the duty cycle (DC) limitations of the adopted ALOHA-based medium access control (MAC) strategy in the industrial, scientific, and medical (ISM) bands. The ISM bands are subjected to an hourly constraint on the number of packet transmissions or inter-message delay, where the devices using higher spreading factors (SFs) can quickly consume the available transmission time. In this paper, we propose and assess the hybrid MAC designs in a LoRa network by combining carrier sense multiple access (CSMA) with ALOHA in two different ways i) exploiting different channel plans for the access mechanisms, ii) relay-assisted access, with devices using small SFs assisting neighboring higher-SF devices with listen-before-talk (LBT) mechanism. Our simulation results reveal that the proposed access strategies lead to a higher packet delivery rate (PDR) as well as lower mean and standard deviation of the communication delay; thus, increasing the overall measurement accuracy.