Organocatalytic Dynamic Kinetic Asymmetric Transformations
2023 (English)In: Dynamic Kinetic Resolution (DKR) and Dynamic Kinetic Asymmetric Transformations (DYKAT) / [ed] J.-E Bäckvall, Georg Thieme Verlag KG, 2023Chapter in book (Refereed)
Abstract [en]
Dynamic kinetic asymmetric transformations (DYKAT) are an important way of converting simple organic molecules into complex small molecules as single diastereo- and enantiomers. Herein we describe selected examples that are catalyzed by small organic molecules, which utilize activation mechanisms similar to enzymes for accomplishing the high stereoselectivity. The research area of DYKAT is growing and remarkable examples for producing important organic molecules and pharmaceuticals are demonstrated. In this context, organocatalysis will play an important role.
Place, publisher, year, edition, pages
Georg Thieme Verlag KG, 2023.
Series
Science of Synthesis
Keywords [en]
dynamic kinetic asymmetric transformation, organocatalysis, highly enantioselective, highly diastereoselective, dual catalysis, hydrogen-bond donation, small-molecule catalysis
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:miun:diva-47581DOI: 10.1055/sos-SD-237-00049ISBN: 9783132453777 (print)ISBN: 9783132453791 (electronic)OAI: oai:DiVA.org:miun-47581DiVA, id: diva2:1736823
2023-02-142023-02-142023-02-14Bibliographically approved