In this paper, a qualitative case study is presented of how a private school in Florida, USA developed innovative responses to the Covid-19 pandemic, while maintaining and sustaining quality, within the school and in relation to global sustainable development goals. The analysis examines the school’s leadership, and how strategic decision making, shared leadership, teaming and collaboration, and the school’s core values and organizational culture were used to adapt and respond to the crisis. Findings from this case study provide insights to better understand how leaders can develop adaptive systems, built on quality management principles, and to foster sustainable practices that are value-based and customer oriented within the Quality 5.0 era. The paper connects to the track’s focus to illustrate and discuss how quality management practices can be used to support sustainable development on the organizational level through adaptability and innovation.