Research suggests that child abuse and neglect may be one of the determining factors in the development of psychopathology because it disrupts the formation of emotional attachment to other people, which leads to emotion dysregulation and alexithymia. This study examined the indirect effect of different types of abuse and neglect on psychopathology through emotion dysregulation accounted by for alexithymia. Sample consisted of 133 college students and staff from United World College Red Cross Nordic. Participants were recruited online via email. A moderated mediation analysis showed a significant conditional indirect effect of childhood emotional abuse, emotional neglect, and physical neglect on psychopathology through emotion dysregulation, with the emotion dysregulation-psychopathology association being increased in magnitude as a function of increased levels of alexithymia. The findings point to the significance of simultaneously investigating emotion dysregulation as a mediator and alexithymia as a moderator within the framework of the association between childhood abuse/neglect and psychopathology in future research. Moreover, these results may serve as an aid in tailoring a transdiagnostic psychotherapeutic treatment that covers alexithymia and emotion regulation difficulties for individuals who show symptoms of comorbid psychopathology with a history of abuse and neglect in childhood.