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Automatic Melanoma Diagnosis in Dermoscopic Imaging Base on Deep Learning System
Mid Sweden University, Faculty of Science, Technology and Media, Department of Electronics Design.
2021 (English)Licentiate thesis, comprehensive summary (Other academic)
Abstract [en]

Melanoma is one of the deadliest forms of cancer. Unfortunately, its incidence rates have been increasing all over the world. One of the techniques used by dermatologists to diagnose melanomas is an imaging modality called dermoscopy. The skin lesion is inspected using a magnification device and a light source. This technique makes it possible for the dermatologist to observe subcutaneous structures that would be invisible otherwise. However, the use of dermoscopy is not straightforward, requiring years of practice. Moreover, the diagnosis is many times subjective and challenging to reproduce. Therefore, it is necessary to develop automatic methods that will help dermatologists provide more reliable diagnoses. 

Since this cancer is visible on the skin, it is potentially detectable at a very early stage when it is curable. Recent developments have converged to make fully automatic early melanoma detection a real possibility. First, the advent of dermoscopy has enabled a dramatic boost in the clinical diagnostic ability to the point that it can detect melanoma in the clinic at the earliest stages. This technology’s global adoption has allowed the accumulation of extensive collections of dermoscopy images. The development of advanced technologies in image processing and machine learning has given us the ability to distinguish malignant melanoma from the many benign mimics that require no biopsy. These new technologies should allow earlier detection of melanoma and reduce a large number of unnecessary and costly biopsy procedures. Although some of the new systems reported for these technologies have shown promise in preliminary trials, a widespread implementation must await further technical progress in accuracy and reproducibility. 

This thesis provides an overview of our deep learning (DL) based methods used in the diagnosis of melanoma in dermoscopy images. First, we introduce the background. Then, this paper gives a brief overview of the state-of-art article on melanoma interpret. After that, a review is provided on the deep learning models for melanoma image analysis and the main popular techniques to improve the diagnose performance. We also made a summary of our research results. Finally, we discuss the challenges and opportunities for automating melanocytic skin lesions’ diagnostic procedures. We end with an overview of a conclusion and directions for the following research plan. 

Place, publisher, year, edition, pages
Mid Sweden University , 2021. , p. 32
Series
Mid Sweden University licentiate thesis, ISSN 1652-8948 ; 180
Keywords [en]
Melanoma classification, computer vision, Deep learning, CNN
National Category
Dermatology and Venereal Diseases Medical Imaging Computer Engineering
Identifiers
URN: urn:nbn:se:miun:diva-41751ISBN: 978-91-89341-00-5 (print)OAI: oai:DiVA.org:miun-41751DiVA, id: diva2:1540186
Presentation
2021-04-23, C312, Holmgatan 10, Sundsvall, 13:00 (English)
Opponent
Supervisors
Available from: 2021-03-29 Created: 2021-03-26 Last updated: 2025-02-09Bibliographically approved
List of papers
1. Automatic Detection of Melanoma with Yolo Deep Convolutional Neural Networks
Open this publication in new window or tab >>Automatic Detection of Melanoma with Yolo Deep Convolutional Neural Networks
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2019 (English)In: 2019 E-Health and Bioengineering Conference (EHB), IEEE, 2019Conference paper, Published paper (Refereed)
Abstract [en]

In the past three years, deep convolutional neural networks (DCNNs) have achieved promising performance in detecting skin cancer. However, improving the accuracy and efficiency of the automatic detection of melanoma is still urgent due to the visual similarity of benign and malignant dermoscopy. There is also a need for fast and computationally effective systems for mobile applications targeting caregivers and homes. This paper presents the You Only Look Once (Yolo) algorithms, which are based on DCNNs applied to the detection of melanoma. The Yolo algorithms comprise YoloV1, YoloV2, and YoloV3, whose methodology first resets the input image size and then divides the image into several cells. According to the position of the detected object in the cell, the network will try to predict the bounding box of the object and the class confidence score. Our test results indicate that the mean average precision (mAP) of Yolo can exceed 0.82 with a training set of only 200 images, proving that this method has great advantages for detecting melanoma in lightweight system applications.

Place, publisher, year, edition, pages
IEEE, 2019
Keywords
Image processing, Melanoma, Yolo, Object Detection
National Category
Electrical Engineering, Electronic Engineering, Information Engineering
Identifiers
urn:nbn:se:miun:diva-38154 (URN)10.1109/EHB47216.2019.8970033 (DOI)000558648300163 ()2-s2.0-85079350541 (Scopus ID)978-1-7281-2603-6 (ISBN)
Conference
IEEE International Conference on e-Health and Bioengineering 2019, Romania, 21-23 November 2019
Funder
European Regional Development Fund (ERDF)
Available from: 2019-12-19 Created: 2019-12-19 Last updated: 2023-01-20Bibliographically approved
2. Deep Melanoma classification with K-Fold Cross-Validation for Process optimization
Open this publication in new window or tab >>Deep Melanoma classification with K-Fold Cross-Validation for Process optimization
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2020 (English)In: 2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA), IEEE, 2020Conference paper, Published paper (Refereed)
Abstract [en]

Deep convolution neural networks (DCNNs) enable effective methods to predict the melanoma classes otherwise found with ultrasonic extraction. However, gathering large datasets in local hospitals in Sweden can take years. Small datasets will result in models with poor accuracy and insufficient generalization ability, which has a great impact on the result. This paper proposes to use a K-Fold cross validation approach based on a DCNN algorithm working on a small sample dataset. The performance of the model is verified via a Vgg16 extracting the features. The experimental results reveal that the model built by the approach proposed in this paper can effectively achieve a better prediction and enhance the accuracy of the model, which proves that K-Fold can achieve better performance on a small skin cancer dataset. 

Place, publisher, year, edition, pages
IEEE, 2020
Keywords
classification, DCNNs, K-Fold, melanoma
National Category
Computer and Information Sciences
Identifiers
urn:nbn:se:miun:diva-39610 (URN)10.1109/MeMeA49120.2020.9137222 (DOI)000612835700073 ()2-s2.0-85088904068 (Scopus ID)978-1-7281-5386-5 (ISBN)
Conference
2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
Available from: 2020-08-17 Created: 2020-08-17 Last updated: 2023-01-20Bibliographically approved
3. Ensembling CNNs for dermoscopic analysis of suspicious skin lesions
Open this publication in new window or tab >>Ensembling CNNs for dermoscopic analysis of suspicious skin lesions
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2021 (English)In: 2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA), IEEE, 2021Conference paper, Published paper (Refereed)
Abstract [en]

Deep Convolution Neural Networks (CNN) enable advanced methods to predict the skin cancer classes through the automatic analysis of digital dermoscopic images. However, small datasets' availability often allows the models to be characterized by low prediction accuracy and poor generalization ability, which significantly influences clinical decisions. This paper proposes to use an original ensembling of multiple CNNs as feature extractors able to detect and measure skin lesions atypical criteria according to the well-known diagnostic method 7-Point Check List. The experimental results show that the Artificial Intelligence-based model can suitably manage the classification uncertainty of the single CNNs and finally distinguish melanomas from benignant nevi. Diagnostic performance is promising in terms of sensitivity and specificity towards a decision-supporting system used by a dermatologist with low experience during clinical practice.

Place, publisher, year, edition, pages
IEEE, 2021
National Category
Medical Engineering
Identifiers
urn:nbn:se:miun:diva-41757 (URN)10.1109/MeMeA52024.2021.9478760 (DOI)000847048100106 ()2-s2.0-85114127281 (Scopus ID)978-1-6654-1914-7 (ISBN)
Conference
MeMeA 2021, The 16th edition of IEEE International Symposium on Medical Measurements and Applications, [DIGITAL] Neuchâtel, Switzerland, June 25-28, 2021.
Available from: 2021-03-29 Created: 2021-03-29 Last updated: 2023-01-20Bibliographically approved

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Nie, Yali

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