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Noise-free quantitative phase imaging in Gabor holography with conditional generative adversarial network
Daegu Gyeongbuk Institute of Science & Technology, 333 Techno Jungang-daero, Hyeonpung-eup, Dalseong-gun, Daegu 42988, South Korea.
Mid Sweden University, Faculty of Science, Technology and Media, Department of Electronics Design. Daegu Gyeongbuk Institute of Science & Technology, 333 Techno Jungang-daero, Hyeonpung-eup, Dalseong-gun, Daegu 42988, South Korea.
Daegu Gyeongbuk Institute of Science & Technology, 333 Techno Jungang-daero, Hyeonpung-eup, Dalseong-gun, Daegu 42988, South Korea.
University of Connecticut.
2020 (English)In: Optics Express, E-ISSN 1094-4087, Vol. 28, no 18, p. 26284-26301Article in journal (Refereed) Published
Abstract [en]

This paper shows that deep learning can eliminate the superimposed twin-image noise in phase images of Gabor holographic setup. This is achieved by the conditional generative adversarial model (C-GAN), trained by input-output pairs of noisy phase images obtained from synthetic Gabor holography and the corresponding quantitative noise-free contrast-phase image obtained by the off-axis digital holography. To train the model, Gabor holograms are generated from digital off-axis holograms with spatial shifting of the real image and twin image in the frequency domain and then adding them with the DC term in the spatial domain. Finally, the digital propagation of the Gabor hologram with Fresnel approximation generates a super-imposed phase image for the C-GAN model input. Two models were trained: a human red blood cell model and an elliptical cancer cell model. Following the training, several quantitative analyses were conducted on the bio-chemical properties and similarity between actual noise-free phase images and the model output. Surprisingly, it is discovered that our model can recover other elliptical cell lines that were not observed during the training. Additionally, some misalignments can also be compensated with the trained model. Particularly, if the reconstruction distance is somewhat incorrect, this model can still retrieve in-focus images. 

Place, publisher, year, edition, pages
2020. Vol. 28, no 18, p. 26284-26301
National Category
Applied Mechanics
Identifiers
URN: urn:nbn:se:miun:diva-39869DOI: 10.1364/OE.398528ISI: 000565713200051Scopus ID: 2-s2.0-85090390927OAI: oai:DiVA.org:miun-39869DiVA, id: diva2:1467705
Available from: 2020-09-16 Created: 2020-09-16 Last updated: 2022-09-15

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Jaferzadeh, Keyvan

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