Facilitating the uptake and use of digital technologies for supporting teaching and learning activities is of importance in schools as organizations. This paper seeks to explore one model for increasing teachers’ practical and conceptual pedagogical digital competence through a school and university collaborative professional development project in pedagogical digital competence (PDC). The project took place in an independent upper secondary school in the north of Sweden over a period of six months. The data materials are comprised of a self-evaluation survey regarding pedagogical digital competence, built on the Technological Pedagogical and Content Knowledge (TPACK)-model, which was completed by the teachers upon the start of the project and at the completion of the project. Interviews were conducted regarding the possibilities and challenges related the project work with the school leader and the two lead teachers in charge of the project work. The findings showed that there appear to be effects related to increasing the uptake and use of digital technologies in teaching as well as in teachers’ pedagogical digital competence. These effects were reported on an interaction level such as teacher and student collaboration, at a course level including course design, and on an organizational level involving teacher collaboration. For facilitating the uptake and use of digital technologies in teaching and learning activities, this project as a model may be seen as one way to support teachers’ pedagogical digital competence, including practical skills, conceptual knowledge and awareness of course design.