Job insecurity and risk of diabetes: A meta-analysis of individual participant dataFinnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
Karolinska Institutet, Stockholm; Stockholm County Council.
University College London, London, United Kingdom; University of Edinburgh, Edinburgh, United Kingdom.
National Research Centre for the Working Environment, Copenhagen, Denmark.
Bispebjerg University Hospital, Copenhagen, Denmark.
Federal Institute for Occupational Safety and Health, Bundesanstalt für Arbeitsschutz und Arbeitsmedizin), Berlin, Germany.
University of Düsseldorf, Düsseldorf, Germany.
National Institute for Health and Welfare, Helsinki, Finland.
Karolinska Institutet; Jönköping University, Jönköping; Stockholm University, Stockholm.
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.
University of Helsinki, Helsinki, Finland.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
University of Helsinki, Helsinki, Finland.
University of Essex, Colchester, United Kingdom.
Frederiksberg University Hospital, Copenhagen, Denmark.
Umeå University, Umeå.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
Danish National Centre for Social Research, Copenhagen, Denmark.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland; University of Turku, Turku, Finland.
University College London, London, United Kingdom.
University of Turku, Turku, Finland; Folkhälsan Research Center, Helsinki, Finland; University of Skövde, Skövde.
University College London, London, United Kingdom; Semmelweis University, Budapest, Hungary.
Stockholm County Council, Stockholm.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland; University of Turku, Turku, Finland; Turku University Hospital, Turku, Finland .
Turku University Hospital, Turku, Finland.
Stockholm County Council, Stockholm.
National Research Centre for the Working Environment, Copenhagen, Denmark; University of Copenhagen, Copenhagen, Denmark.
Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland.
University College London, London, United Kingdom; Finnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland; University of Helsinki, Helsinki, Finland.
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2016 (English)In: CMJA. Canadian Medical Association Journal. Onlineutg. Med tittel: ECMAJ. ISSN 1488-2329, ISSN 0820-3946, E-ISSN 1488-2329, Vol. 188, no 17-18, p. E447-E455Article in journal (Refereed) Published
Abstract [en]
Background: Job insecurity has been associated with certain health outcomes. We examined the role of job insecurity as a risk factor for incident diabetes. Methods: We used individual participant data from 8 cohort studies identified in 2 open-access data archives and 11 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. We calculated study-specific estimates of the association between job insecurity reported at baseline and incident diabetes over the follow-up period. We pooled the estimates in a meta-analysis to produce a summary risk estimate. Results: The 19 studies involved 140 825 participants from Australia, Europe and the United States, with a mean follow-up of 9.4 years and 3954 incident cases of diabetes. In the preliminary analysis adjusted for age and sex, high job insecurity was associated with an increased risk of incident diabetes compared with low job insecurity (adjusted odds ratio [OR] 1.19, 95% confidence interval [CI] 1.09-1.30). In the multivariable-adjusted analysis restricted to 15 studies with baseline data for all covariates (age, sex, socioeconomic status, obesity, physical activity, alcohol and smoking), the association was slightly attenuated (adjusted OR 1.12, 95% CI 1.01-1.24). Heterogeneity between the studies was low to moderate (age- and sex-adjusted model: I2 = 24%, p = 0.2; multivari-able-adjusted model: I2 = 27%, p = 0.2). In the multivariable-adjusted analysis restricted to high-quality studies, in which the diabetes diagnosis was ascertained from electronic medical records or clinical examination, the association was similar to that in the main analysis (adjusted OR 1.19, 95% CI 1.04-1.35). Interpretation: Our findings suggest that self-reported job insecurity is associated with a modest increased risk of incident diabetes. Health care personnel should be aware of this association among workers reporting job insecurity.
Place, publisher, year, edition, pages
2016. Vol. 188, no 17-18, p. E447-E455
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:miun:diva-29818DOI: 10.1503/cmaj.150942ISI: 000390417900015PubMedID: 27698195Scopus ID: 2-s2.0-85002388938OAI: oai:DiVA.org:miun-29818DiVA, id: diva2:1061559
Note
Funding details: K013351, MRC, Medical Research Council
The IPD-Work Consortium is supported by Nord-Forsk (grant no. 75021), the Nordic Programme on Health and Welfare; the EU New OSH ERA Research Programme (funded by the Finnish Work Environment Fund; the Swedish Research Council for Health, Working Life and Welfare; the German Social Accident Insurance; and the Danish National Research Centre for the Working Environment); the Academy of Finland (grant nos. 132944 and 258598); and the Bupa UK Foundation (grant no. 22094477). Mika Kivimäki is supported by the Medical Research Council (grant no. K013351) and the Economic and Social Research Council, UK. Funding bodies for the participating cohort studies are listed on their websites. The study sponsors had no role in the design of the study, the collection, analysis or interpretation of data, the writing of the report or the decision to submit the article for publication.
2017-01-032017-01-032020-07-10Bibliographically approved