miun.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Antimicrobial and Cytotoxic Activities of the Crude Extracts and Isolated Compounds of Xylocarpus mollucensis
University of Dhaka, Bangladesh .
University of Dhaka, Bangladesh .
University of Dhaka, Bangladesh .
University of Dhaka, Bangladesh .
2008 (English)In: Dhaka University Journal of Pharmaceutical Sciences, Vol. 6, no 2, p. 109-112Article in journal (Refereed) Published
Abstract [en]

The fractionated crude extracts and three isolated pure compounds XM-1, XM-2 and XM-3 from stem bark of Xylocarpus mollucensis were screened for their antibacterial and antifungal activities and cytotoxicity against brine shrimp nauplii. Petroleum ether, ethyl acetate (EtOAc) and methanol (MeOH) extracts and the compounds isolated from EtOAc fractions were studied for their antimicrobial activities. Cytotoxic activities were conducted only with EtOAc extract and its selected fractions. The EtOAc extract showed promising antimicrobial activities against all the gram positive and gram negative bacteria whereas petroleum ether extract showed moderate activities and the MeOH extract did not show any antimicrobial activities. The isolated pure compounds XM-1, XM-2 and XM-3, whose structures were not elucidated, exhibited activities against most of the bacterial strains. The cytotoxicity towards brine shrimp nauplii of the crude EtOAC extract and its selected fractions were studied. The LC50 values of the EtoAc extract was 12.6 µg/ml and for the fractions 2, 5, 8 and 13 were 17.78, 13.34, 14.13 and 15.85 µg/ml, respectively.

Place, publisher, year, edition, pages
Dhaka, Bangladesh, 2008. Vol. 6, no 2, p. 109-112
National Category
Biochemistry and Molecular Biology
Identifiers
URN: urn:nbn:se:miun:diva-34752DOI: 10.3329/dujps.v6i2.685OAI: oai:DiVA.org:miun-34752DiVA, id: diva2:1257727
Available from: 2018-10-22 Created: 2018-10-22 Last updated: 2018-11-15Bibliographically approved

Open Access in DiVA

fulltext(35 kB)151 downloads
File information
File name FULLTEXT01.pdfFile size 35 kBChecksum SHA-512
9cabf83f20134112b7eace49960d48bcf3bd91c7d49f5ab127ac9e8c3b7e87d1001f76492281bb73ba172569fd115fc51a80893d103bb2be9c6e3cfb05829091
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Authority records BETA

Rahman, Hafizur

Search in DiVA

By author/editor
Rahman, Hafizur
Biochemistry and Molecular Biology

Search outside of DiVA

GoogleGoogle Scholar
Total: 151 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 166 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf