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Ethnic differences in the risk factors and severity of coronary artery disease: a patient-based study in Iran
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences. Tehran University of Medical Sciences, Tehran, Iran.
Mid Sweden University, Faculty of Human Sciences, Department of Psychology.ORCID iD: 0000-0002-4116-5501
Teheran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Mid Sweden University, Faculty of Human Sciences, Department of Health Sciences.ORCID iD: 0000-0001-5221-9504
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2017 (English)In: Journal of Racial and Ethnic Health Disparities, ISSN 2197-3792Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background Diverse ethnic groups may differ regarding

the risk factors and severity of coronary artery disease

(CAD). This study sought to assess the association between

ethnicity and CAD risk and severity in six major

Iranian ethnic groups.

Methods In this study, 20,165 documented coronary artery

disease patients who underwent coronary angiography

at a tertiary referral heart center were recruited. The

demographic, laboratory, clinical, and risk factor data of

all the patients were retrieved. The Gensini score (an

indicator of CAD severity) was calculated for all, and

the risk factors and severity of CAD were compared

between the ethnical groups, using adjusted standardized

residuals, Kruskal–Wallis test, and multivariable regression

analysis.

Results The mean age of the participants (14,131

[70.1%] men and 6034 [29.9%] women) was

60.7 ± 10.8 years. The Fars (8.7%) and Gilak (8.6%)

ethnic groups had the highest prevalence of ≥4 simultaneous

risk factors. The mean Gensini score was the

highest for the Gilaks (77.1 ± 55.9) and the lowest

among the Lors (67.5 ± 52.8). The multivariable regression

analysis showed that the Gilaks had the worst severity

(β 0.056, 95% CI 0.009 to 0.102; P = 0.018),

followed by the Torks (β 0.032, 95% CI 0.005 to 0.059;

P = 0.020). Meanwhile, the Lors showed the lowest

severity (β −0.087, 95% CI −0.146 to −0.027;

P = 0.004).

Conclusions This study found that there was heterogeneity in

CAD severity and a diverse distribution in its well-known

traditional risk factors among major Iranian ethnic groups.

Place, publisher, year, edition, pages
Springer Berlin/Heidelberg, 2017.
Keyword [en]
Health status disparities Ethnicity Coronary heart disease
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:miun:diva-31406DOI: 10.1007/s40615-017-0408-3OAI: oai:DiVA.org:miun-31406DiVA: diva2:1133514
Available from: 2017-08-16 Created: 2017-08-16 Last updated: 2017-08-22Bibliographically approved

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Abbasi, Seyed HSundin, ÖrjanSoares, JoaquimMacassa, Gloria

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CiteExportLink to record
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