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Nonsearch paradigm for large-scale parameter-identification problems in dynamical systems related to oncogenic hyperplasia
Mittuniversitetet, Fakulteten för naturvetenskap, teknik och medier, Institutionen för informationsteknologi och medier.
2006 (engelsk)Inngår i: Proceedings of the 22nd IFIP TC7 Conference held from July 18–22, 2005, in Turin, Italy, 2006, Vol. 202, s. 269-278Konferansepaper, Publicerat paper (Fagfellevurdert)
Abstract [en]

In many engineering and biomedical problems there is a need to identify parameters of the systems from experimental data. A typical example is the biochemical-kinetics systems describing oncogenic hyperplasia where the dynamical model is nonlinear and the number of the parameters to be identified can reach a few hundreds. Solving these large-scale identification problems by the local- or global-search methods can not be practical because of the complexity and prohibitive computing time. These difficulties can be overcome by application of the non-search techniques which are much less computation- demanding. The present work proposes key components of the corresponding mathematical formulation of the nonsearch paradigm. This new framework for the nonlinear large-scale parameter identification specifies and further develops the ideas of the well-known approach of A. Krasovskii. The issues are illustrated with a concise analytical example. The new results and a few directions for future research are summarized in a dedicated section.

sted, utgiver, år, opplag, sider
2006. Vol. 202, s. 269-278
Emneord [en]
Biochemical kinetics, Identification, Krasovskii method, Non-search parameter, Nonlinear dynamic system
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Identifikatorer
URN: urn:nbn:se:miun:diva-28999DOI: 10.1007/0-387-33882-9_25Scopus ID: 2-s2.0-33750442538ISBN: 0387338810 (tryckt)ISBN: 9780387338811 (tryckt)OAI: oai:DiVA.org:miun-28999DiVA, id: diva2:998791
Konferanse
IFIP International Federation for Information Processing
Tilgjengelig fra: 2016-09-30 Laget: 2016-09-30 Sist oppdatert: 2016-09-30bibliografisk kontrollert

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