miun.sePublications
Change search
Link to record
Permanent link

Direct link
BETA
Persson, Gerd
Publications (8 of 8) Show all publications
Svanedal, I., Persson, G., Norgren, M. & Edlund, H. (2014). Interactions in Mixed Micellar Systems of an Amphoteric Chelating Surfactant and Ionic Surfactants. Langmuir, 30(5), 1250-1256
Open this publication in new window or tab >>Interactions in Mixed Micellar Systems of an Amphoteric Chelating Surfactant and Ionic Surfactants
2014 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 30, no 5, p. 1250-1256Article in journal (Refereed) Published
Abstract [en]

Mixtures of ionic surfactants and the chelating surfactant 2-dodecyldiethylenetriaminepentaacetic acid (4-C12-DTPA) have been examined in terms of interactions in mixed micellar systems. The amphoteric 4-C12-DTPA is zwitterionic with a negative net charge at the studied pH levels. The investigated ionic surfactants were the cationic dodecyltrimethylammonium chloride (DoTAC), the anionic sodium dodecyl sulfate (SDS), and the zwitterionic dimethyldodecylamine-N-oxide (DDAO). The surfactants all have the same hydrophobic chain lengths, and the results are evaluated in terms of headgroup interactions. 4-C12-DTPA interacts with different ionic surfactants by accepting or donating protons to the aqueous solution to increase the attractive interactions between the two surfactants; i.e., the protonation equilibrium of 4-C12-DTPA is shifted in different directions depending on whether there are predominant repulsions between positively or negatively charged groups in the mixed micelles. This was monitored by measuring pH vs concentration in the mixed systems. By measuring the pH, it was also possible to study the shift in the protonation equilibrium at increasing concentration, as the composition in the micelles approaches the composition in the total solution. Following the approach of Rubingh's regular solution theory, the interaction parameter β for mixed micelle formation was calculated from the cmc values determined by NMR diffusometry. Synergism in mixed micelle formation and negative β parameters were found in all of the investigated systems. As expected, the most negative β parameter was found in the mixture with DoTAC, followed by DDAO and SDS. The self-diffusion in the 4-C12-DTPA/DoTAC system was also discussed. The self-diffusion coefficient vs concentration plots show two distinctly different curves, depending on the surfactant that is present in excess.

National Category
Physical Chemistry
Identifiers
urn:nbn:se:miun:diva-21404 (URN)10.1021/la404656b (DOI)000331344000008 ()2-s2.0-84894189855 (Scopus ID)
Available from: 2014-02-20 Created: 2014-02-20 Last updated: 2017-12-06Bibliographically approved
Svanedal, I., Boija, S., Almesåker, A., Persson, G., Andersson, F., Hedenström, E., . . . Edlund, H. (2014). Metal Ion Coordination, Conditional Stability Constants and Solution Behavior of Chelating Surfactant Metal Complexes. Langmuir, 30(16), 4605-4612
Open this publication in new window or tab >>Metal Ion Coordination, Conditional Stability Constants and Solution Behavior of Chelating Surfactant Metal Complexes
Show others...
2014 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 30, no 16, p. 4605-4612Article in journal (Refereed) Published
Abstract [en]

Coordination complexes of some divalent metal ions with the DTPA (diethylenetriaminepentaacetic acid)-based chelating surfactant 2-dodecyldiethylenetriaminepentaacetic acid (4-C12-DTPA) have been examined in terms of chelation and solution behavior. The headgroup of 4-C 12-DTPA contains eight donor atoms that can participate in the coordination of a metal ion. Conditional stability constants for five transition metal complexes with 4-C12-DTPA were determined by competition measurements between 4-C12-DTPA and DTPA, using electrospray ionization mass spectrometry (ESI-MS). Small differences in the relative strength between the coordination complexes of DTPA and 4-C12-DTPA indicated that the hydrocarbon tail only affected the chelating ability of the headgroup to a limited extent. The coordination of Cu2+ ions was investigated in particular, using UV-visible spectroscopy. By constructing Job's plots, it was found that 4-C12-DTPA could coordinate up to two Cu2+ ions. Surface tension measurements and NMR diffusometry showed that the coordination of metal ions affected the solution behavior of 4-C 12-DTPA, but there were no specific trends between the studied divalent metal complexes. Generally, the effects of the metal ion coordination could be linked to the neutralization of the headgroup charge of 4-C 12-DTPA, and the resulting reduced electrostatic repulsions between adjacent surfactants in micelles and monolayers. The pH vs concentration plots, on the other hand, showed a distinct difference between 4-C12-DTPA complexes of the alkaline earth metals and the transition metals. This was explained by the difference in coordination between the two groups of metal ions, as predicted by the hard and soft acid and base (HSAB) theory.

National Category
Physical Chemistry
Identifiers
urn:nbn:se:miun:diva-21401 (URN)10.1021/la5002336 (DOI)000335297300011 ()2-s2.0-84899622360 (Scopus ID)
Available from: 2014-02-20 Created: 2014-02-20 Last updated: 2017-12-06Bibliographically approved
Svanedal, I., Persson, G., Norgren, M. & Edlund, H. (2013). Anomalies in Solution Behavior of an Alkyl Aminopolycarboxylic Chelating Surfactant. Langmuir, 29(45), 13708-13716
Open this publication in new window or tab >>Anomalies in Solution Behavior of an Alkyl Aminopolycarboxylic Chelating Surfactant
2013 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 29, no 45, p. 13708-13716Article in journal (Refereed) Published
Abstract [en]

The solution behavior of a DTPA (diethylenetriaminepentaacetic acid)-based chelating surfactant, 4-C12-DTPA, has beenstudied by tensiometry and NMR diffusometry. In the absence of metalions, the eight donor atoms in the headgroup are titrating, and thecharge of the headgroup can thus be tuned by altering the pH. 4-C12-DTPA changes from cationic at very low pH, over a number ofzwitterionic species as the pH is increased, and eventually becomesanionic at high pH. Around the isoelectric point, the chelatingsurfactant precipitated. The solution properties, studied above thesolubility gap, were found strongly pH dependent. When increasing theamount of negative charges in the headgroup, by increasing the pH, theadsorption efficiency was reduced and the cmc was increased. Anoptimum in surface tension reduction was found at pH 5, due to aproper balance between protonated and dissociated groups. Anomaliesbetween surface tension measurements and NMR diffusometry in determination of cmc revealed a more complex relationbetween surface tension, surface coverage, and cmc than usually considered, which is not in line with the common interpretationof the Gibbs adsorption equation. At some of the investigated pH levels, measurements of bulk pH could confirm the location ofcmc, due to the increased protonation of micelles compared to monomers in solution. The adsorption of monomers to the air−water interface showed unusually slow time dependence, evident from decreasing surface tension for several hours. This isexplained by rearrangements of the large head groups to reduce the headgroup area and increase the packing parameter.

National Category
Physical Chemistry
Identifiers
urn:nbn:se:miun:diva-20289 (URN)10.1021/la4024508 (DOI)000327044600007 ()2-s2.0-84887573543 (Scopus ID)
Available from: 2013-11-22 Created: 2013-11-22 Last updated: 2017-12-06Bibliographically approved
Persson, G., Edlund, H., Hedenström, E. & Lindblom, G. (2004). Phase Behavior of 1-Alkylpyridinium Octane-1-sulfonates: Effect of the 1-Alkylpyridinium Counterion Size. Langmuir, 20(4), 1168-1179
Open this publication in new window or tab >>Phase Behavior of 1-Alkylpyridinium Octane-1-sulfonates: Effect of the 1-Alkylpyridinium Counterion Size
2004 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 20, no 4, p. 1168-1179Article in journal (Refereed) Published
Abstract [en]

The temperature-versus-composition phase diagrams of eight different 1-alkylpyridinium octane-1-sulfonates (APOSs) in water were studied by 1H NMR, 2H NMR, pulsed gradient spin-echo NMR, small-angle X-ray diffraction, differential scanning calorimetry, surface tension and conductivity measurements, and polarizing microscopy. The number of carbons (nc) in the hydrocarbon chain of the pyridinium counterions was varied from nc = 1 to nc = 8 to study how the phase behavior of the APOS/2H2O systems was affected by a change in the chain length of the counterion. The sodium octane-1-sulfonate (NaOS)/water system was used as a reference. This system formed an isotropic micellar solution (L1) phase and a normal hexagonal (HI) phase. All APOSs were readily soluble in water and formed L1 phases. The surface tension above the critical micelle concentration for nc between 1 and 3 was higher than that for NaOS, and it decreased steadily for the different APOSs with increasing chain length. The area per molecule at the air/solution interfaces was rather constant at 68 Å2 for nc between 1 and 7. For 1-octylpyridinium octane-1-sulfonate (OPOS), it was about 5 Å2 smaller, which was just outside the estimated error. However, the smallest area was obtained for NaOS. At higher surfactant concentrations, liquid crystalline phases formed. Both cubic and HI phases were found for nc = 1 and 2, while for nc between 3 and 5 only an HI phase was observed. HI and lamellar liquid crystalline (L) phases formed for nc = 6 and 7. The only liquid crystalline phase found in the OPOS system was a L phase. The NaOS HI phase was the only liquid crystalline phase that showed a linear relation between the 2H2O NMR quadrupolar splitting (W) and Xsurf/XW, where Xsurf and XW are the mole fractions of surfactant and water. The OPOS lamellae were found to be much thinner than expected, indicating a defect lamellar structure. This was further supported by the behavior of the quadrupolar splitting of deuterated OPOS. The anomalous behaviors of the 2H2O NMR quadrupolar splitting observed in the L phases of 1-heptylpyridinium octane-1-sulfonate and OPOS were interpreted in terms of changes in the population of the water molecules residing in different sites combined with a continuous rearrangement of the lamellae surface with the possible development of holes. The appearances of the phase diagrams were discussed in terms of surfactant molecular geometry and the packing of the amphiphiles in the aggregates formed.

Keywords
surfactant self-assembly
National Category
Chemical Sciences
Identifiers
urn:nbn:se:miun:diva-842 (URN)10.1021/la035213r (DOI)000189013400026 ()15803692 (PubMedID)2-s2.0-1542285775 (Scopus ID)1715 (Local ID)1715 (Archive number)1715 (OAI)
Available from: 2008-09-30 Created: 2008-09-30 Last updated: 2017-12-13Bibliographically approved
Persson, G., Edlund, H. & Lindblom, G. (2004). Phase behaviour of the 1-monooleoyl-rac-glycerol/n-octyl-beta-D-glucoside/water system. In: Miguel, MG; Burrows, HD (Ed.), TRENDS IN COLLOID AND INTERFACE SCIENCE XVI: . Paper presented at 15th Conference of the European-Colloid-and-Interface-Society, Sep 16-21, 2001, Coimbra, Portugal (pp. 36-39). Springer, 123
Open this publication in new window or tab >>Phase behaviour of the 1-monooleoyl-rac-glycerol/n-octyl-beta-D-glucoside/water system
2004 (English)In: TRENDS IN COLLOID AND INTERFACE SCIENCE XVI / [ed] Miguel, MG; Burrows, HD, Springer, 2004, Vol. 123, p. 36-39Conference paper, Published paper (Refereed)
Abstract [en]

Obtaining high-quality crystals for X-ray diffraction from membrane proteins has proven to be a difficult task. One recently presented method utilises the cubic phases formed by 1-monooleoyl-rac-glycerol (MO). Removing the proteins from their native environment requires the use of surfactants. One commonly used surfactant is n-octyl-beta-D-glucopyranoside (OG). Using NMR techniques and visual observations, the ternary phase diagram of MO/OG/(H2O)-H-2 was outlined at 25 degreesC. The preliminary data show that all phases present in the binary systems at this temperature are also found in the ternary. Further, at the OG-rich side, an additional phase that appears to be hexagonal occurs. Addition of minor amounts (approximate to1.5 wt/wt %) of OG converts the cubic phases of MO to a lamellar structure, while the OG-rich cubic phase is able to dissolve about 15 wt/wt % MO. OG in water forms a large micellar solution phase;. Increasing the MO concentration at constant water content leads to a series of two- and three-phase areas in which one or two phases are in equilibrium with almost pure water.

Place, publisher, year, edition, pages
Springer, 2004
Series
PROGRESS IN COLLOID AND POLYMER SCIENCE, ISSN 0340-255X ; 12
Keywords
MEMBRANE-PROTEIN CRYSTALLIZATION; LIPIDIC CUBIC PHASES; DIAGRAM
National Category
Physical Sciences
Identifiers
urn:nbn:se:miun:diva-13490 (URN)10.1007/b11618 (DOI)000223033700009 ()3-540-00553-6 (ISBN)
Conference
15th Conference of the European-Colloid-and-Interface-Society, Sep 16-21, 2001, Coimbra, Portugal
Available from: 2011-04-08 Created: 2011-04-08 Last updated: 2014-04-23Bibliographically approved
Persson, G., Edlund, H., Amenitsch, H., Laggner, P. & Lindblom, G. (2003). The 1-monooleoyl-rac-glycerol/n-octyl-beta-D-glucoside/water system: Phase diagram and phase structures determined by NMR and X-ray diffraction. Langmuir, 19(14), 5813-5822
Open this publication in new window or tab >>The 1-monooleoyl-rac-glycerol/n-octyl-beta-D-glucoside/water system: Phase diagram and phase structures determined by NMR and X-ray diffraction
Show others...
2003 (English)In: Langmuir, ISSN 0743-7463, Vol. 19, no 14, p. 5813-5822Article in journal (Refereed) Published
Abstract [en]

Using SAXD and NMR techniques as well as visual observations, a detailed study of the extension of the phase regions and their structures has been performed for the ternary system 1-monooleoyl-rac-glycerol (MO)/n-octyl-β-d-glucopyranoside (OG)/2H2O at 25 °C. OG in water forms a large region of a micellar solution phase, in which substantial amounts of MO can be dissolved. Increasing the MO concentration at constant water content results in the formation of two- and three-phase areas, consisting of liquid, lamellar, or cubic phases in equilibrium with a very dilute water/OG solution. Besides the different phases previously reported for the binary systems, an additional hexagonal phase occurs at high OG contents. Addition of minor amounts (≈1.5 wt %) of OG converts the cubic phases present in the MO/2H2O system to an Lα phase, while the cubic phase in the OG/2H2O system is able to dissolve as much as 15 wt % MO. Since a major part of the phase diagram consists of planar bilayers, it is concluded that for most MO/OG ratios the spontaneous curvature is close to zero. The reason for this is discussed in terms of the molecular packing of MO and OG.

Keywords
surfaktanter, x-ray, NMR
National Category
Chemical Sciences
Identifiers
urn:nbn:se:miun:diva-4637 (URN)10.1021/la034492f (DOI)000183994400035 ()2-s2.0-0037703382 (Scopus ID)606 (Local ID)606 (Archive number)606 (OAI)
Available from: 2008-09-30 Created: 2008-09-30 Last updated: 2016-10-24Bibliographically approved
Persson, G., Edlund, H. & Lindblom, G. (2003). Thermal Behaviour of Cubic Phases Rich in 1-monooleoyl-rac-glycerol in the ternary system 1-monooleoyl-rac-glycerol / n-octyl-b-D-glucoside / Water.. European Journal of Biochemistry, 270(1), 56-65
Open this publication in new window or tab >>Thermal Behaviour of Cubic Phases Rich in 1-monooleoyl-rac-glycerol in the ternary system 1-monooleoyl-rac-glycerol / n-octyl-b-D-glucoside / Water.
2003 (English)In: European Journal of Biochemistry, ISSN 0014-2956, Vol. 270, no 1, p. 56-65Article in journal (Refereed) Published
Abstract [en]

Using synchrotron X-ray diffraction the thermal behaviour was studied of the cubic phases in the 1-monooleoyl-rac -glycerol (MO)/n-octyl-beta-d-glucopyranoside (OG)/(2) H-2 O system with 58 or 45 wt % MO concentration and varying OG/(H2O)-H-2 contents. These MO contents correspond to a Pn3m cubic single-phase or a Pn3m cubic phase in excess water on the binary MO/water axis of the ternary phase diagram. The cubic liquid crystalline phases are stable with small fractions of OG, while higher OG concentrations trigger a cubic-to-lamellar phase transition. Moreover, with increasing OG concentration the initial Pn3m structure is completely converted to an Ia3d structure prior to the L-alpha phase being formed. Upon heating this effect is reversed, resulting in an Ia3d -to-Pn3m phase transition. For some samples additional peaks were observed in the diffractograms upon heating, resulting from the metastability notoriously shown by bicontinuous cubic phases. This judgement is supported by the fact that upon cooling these peaks were absent. Remarkably, both the Ia3d and the Pn3m cubic structures could be in equilibrium with excess water in this ternary system. A comparison is made with previous results on n -dodecyl-beta-d-maltoside (DM), showing that cubic phases with OG have higher thermal and compositional stability than with DM

Keywords
surfaktanter
National Category
Chemical Sciences
Identifiers
urn:nbn:se:miun:diva-1839 (URN)000179924900007 ()2-s2.0-0037219974 (Scopus ID)603 (Local ID)603 (Archive number)603 (OAI)
Available from: 2008-09-30 Created: 2008-09-30 Last updated: 2016-10-21Bibliographically approved
Carlsson, H., Edlund, H., Persson, G. & Lindström, B. (1996). Competition Between Monovalent and Divalent Counterions in a Surfactant / Water System. Journal of Colloid and Interface Science, 180(2), 598-604
Open this publication in new window or tab >>Competition Between Monovalent and Divalent Counterions in a Surfactant / Water System
1996 (English)In: Journal of Colloid and Interface Science, ISSN 0021-9797, E-ISSN 1095-7103, Vol. 180, no 2, p. 598-604Article in journal (Refereed) Published
Abstract [en]

Competition between mono- and divalent ions in the association of counterions to the headgroups of amphiphiles was studied in one surfactant system with organic counterions (piperidine+/piperazine2+octanesulfonate) and one with inorganic counterions (Na+/Ca2+octyl sulfate). By conductivity and13C NMR chemical shift measurements the critical micelle concentration (CMC) was found to decrease drastically when small amounts of divalent counterions were present in the system. Self-diffusion coefficients of surfactant ions and organic counterions were measured in the micellar phase by the Fourier transform pulsed-gradient spin-echo (FT-PGSE) NMR method. The degree of counterion binding in the micellar system with piperidine+/piperazine2+counterions was obtained from FT-PGSE NMR measurements. It was observed that the divalent counterions were more strongly bound than the monovalent counterions. The experimental results were compared with theoretical Poisson–Boltzmann calculations. The cell model was used to study the electrostatic effects. Good agreement between electrostatic theory and experiment was observed; however, an attractive force exists between the monovalent piperidine counterions and the micelle, probably because of hydrophobic interactions.

National Category
Chemical Sciences
Identifiers
urn:nbn:se:miun:diva-8452 (URN)10.1006/jcis.1996.0341 (DOI)
Available from: 2009-01-26 Created: 2009-01-26 Last updated: 2017-12-14Bibliographically approved
Organisations

Search in DiVA

Show all publications